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Collaboration Revenue - Additional Information (Details) | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2026 USD ($) | Jun. 30, 2025 USD ($) | Jun. 30, 2026 USD ($) Target | Jun. 30, 2025 USD ($) | Dec. 31, 2025 USD ($)
Research And Development Arrangement Contract To Perform For Others [Line Items] |  |  |  |  |
Research and development expense | $ 30,994,000 | $ 34,664,000 | $ 57,807,000 | $ 59,719,000 |
Accounts receivable outstanding | 149,000 |  | $ 149,000 |  | $ 0
Merck Agreement |  |  |  |  |
Research And Development Arrangement Contract To Perform For Others [Line Items] |  |  |  |  |
Number of collaboration targets | Target |  |  | 2 |  |
Non-refundable and non-creditable upfront fee |  |  | $ 8,000,000 |  |
Payable upon selection of second collaboration target | 8,000,000 |  | 8,000,000 |  |
Milestone payments |  |  | 285,000,000 |  |
Revenue recognized | 0 | $ 0 | 0 | $ 0 |
Merck Agreement | Maximum |  |  |  |  |
Research And Development Arrangement Contract To Perform For Others [Line Items] |  |  |  |  |
Milestone payments per collaboration target |  |  | 142,500,000 |  |
Milestone payments upon successful completion of certain commercial milestones |  |  | 350,000,000 |  |
BMS Agreement |  |  |  |  |
Research And Development Arrangement Contract To Perform For Others [Line Items] |  |  |  |  |
Non-refundable and non-creditable upfront fee |  |  | 15,000,000 |  |
Upfront payment received |  |  | 15,000,000 |  |
Developmental milestone |  |  | 35,000,000 |  |
Revenue recognized | 10,300,000 |  | 14,000,000 |  |
Transaction price agreement initial determined amount |  |  | 56,700,000 |  |
Research and development expense |  |  | 6,700,000 |  |
Transaction price allocated for performance obligations |  |  | 42,700,000 |  |
Deferred revenue | 36,100,000 |  | 36,100,000 |  |
Deferred revenue current | 35,100,000 |  | 35,100,000 |  |
Accounts receivable outstanding | $ 100,000 |  | $ 100,000 |  |
Remaining term of research services revenue recognized | 1 year 3 months 18 days |  | 1 year 3 months 18 days |  |
BMS Agreement | Maximum |  |  |  |  |
Research And Development Arrangement Contract To Perform For Others [Line Items] |  |  |  |  |
Milestone payments upon successful completion of certain commercial milestones |  |  | $ 750,000,000 |  |

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