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Summary of Significant Accounting Policies - Additional Information (Detail) |  | 1 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Mar. 09, 2018 | Oct. 31, 2017 USD ($) | Dec. 31, 2019 USD ($) Segment | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($) | Jan. 01, 2019 USD ($)
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Reverse stock split |  |  | the Company effected a reverse split of all shares of its common and preferred stock at a ratio of 1-for-3.96 |  |  |
Reverse stock split ratio | 0.2525 |  |  |  |  |
Number of operating segments | Segment |  |  | 1 |  |  |
Number of reportable segments | Segment |  |  | 1 |  |  |
Accumulated deficit |  |  | $ (205,326,000) | $ (122,828,000) |  |
Minimum |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Property and equipment, estimated useful lives |  |  | 1 year |  |  |
Impairment charges |  |  | $ 0 | 0 |  |
Maximum |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Property and equipment, estimated useful lives |  |  | 5 years |  |  |
Taiho Agreement | Taiho Pharmaceutical Co Ltd |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Accumulated deficit |  |  |  | 2,200,000 |  |
Non-refundable upfront research and development fees term |  |  | 5 years |  |  |
Transaction price |  |  |  |  |  | $ 35,000,000
Non refundable and non creditable upfront cash payment received |  |  | $ 35,000,000 |  |  |
Payment received for license agreement |  | $ 5,000,000 | 5,000,000 | 5,000,000 | $ 25,000,000 |
Additional payment to be received for license agreement |  |  | $ 5,000,000 | 5,000,000 |  |
Net reduction to deferred revenue |  |  |  | $ 2,200,000 |  |
Estimated performance period |  |  | 5 years | 4 years | 5 years |
Before Adoption of Topic 606 |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Accumulated deficit |  |  |  | $ (122,828,000) |  |
Before Adoption of Topic 606 | Taiho Agreement | Taiho Pharmaceutical Co Ltd |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Additional payment to be received for license agreement |  |  |  | $ 5,000,000 |  |
Non-refundable, non-creditable cash payment received |  |  |  |  | $ 25,000,000 |
ASC 606 |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Accumulated deficit |  |  |  |  |  | (120,616,000)
Non-refundable upfront research and development fees term |  |  | 5 years |  |  |
ASC 606 | Adjustment due to The Adoption of Topic 606 |  |  |  |  |  |
Significant Accounting Policies [Line Items] |  |  |  |  |  |
Accumulated deficit |  |  |  |  |  | $ 2,212,000

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