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Convertible Preferred Stock and Stockholders' Equity (Deficit) - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 1 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | ---
Jul. 13, 2020 | Jun. 30, 2020 | Dec. 31, 2020 | Dec. 31, 2018 | Dec. 31, 2019 | Dec. 31, 2017
Class Of Stock [Line Items] |  |  |  |  |  |
Capital stock shares authorized |  |  | 410,000,000 |  |  |
Common stock, shares authorized |  |  | 400,000,000 |  | 400,000,000 |
Preferred stock, shares authorized |  |  | 10,000,000 |  | 10,000,000 |
Common stock, par value |  |  | $ 0.0001 |  | $ 0.0001 |
Preferred stock, par value |  |  | $ 0.0001 |  | $ 0.0001 |
Net proceeds from public offering after deducting underwriting discounts, commissions and other offering expenses |  |  | $ 433,776 |  |  |
Common stock share value |  |  | $ 326,246 | $ 124,735 |  |
Convertible Preferred Stock |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |
Convertible preferred stock, shares outstanding |  |  | 0 |  | 0 | 30,459,574
Stock Purchase Agreement | Gilead |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |
Common stock shares issued | 5,963,029 |  |  |  |  |
Shares issued, price per share | $ 33.54 |  |  |  |  |
Net proceeds from public offering after deducting underwriting discounts, commissions and other offering expenses | $ 107,500 |  |  |  |  |
Common stock share value | 200,000 |  | $ 107,468 |  |  |
Purchase price of common stock allocation to performance obligation | 90,600 |  |  |  |  |
Deferred offering expenses | $ 1,900 |  |  |  |  |
May 2020 Public Offering |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |
Common stock shares issued |  | 12,650,000 |  |  |  |
Shares issued, price per share |  | $ 27.50 |  |  |  |
Net proceeds from public offering after deducting underwriting discounts, commissions and other offering expenses |  | $ 326,200 |  |  |  |
Base Shares |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |
Common stock shares issued |  | 11,000,000 |  |  |  |
Underwriters Option Exercise |  |  |  |  |  |
Class Of Stock [Line Items] |  |  |  |  |  |
Common stock shares issued |  | 1,650,000 |  |  |  |

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