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Net Loss per Share | 12 Months Ended
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Dec. 31, 2020
Earnings Per Share [Abstract] |
Net Loss per Share | Note 10. Net Loss per Share The following table sets forth the computation of basic and diluted net loss per share (in thousands, except share and per share data):
|  | Year Ended December 31, |
|  | 2020 |  |  | 2019 |  |  | 2018 |
Numerator: |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | $ | (122,858 | ) |  | $ | (84,710 | ) |  | $ | (49,594 | )
Denominator: |  |  |  |  |  |  |  |  |  |  |  |
Weighted-average common shares outstanding |  |  | 56,354,059 |  |  |  | 45,385,489 |  |  |  | 36,357,336 |
Less: weighted-average common shares subject to repurchase |  |  | (1,566,941 | ) |  |  | (1,559,498 | ) |  |  | (1,739,099 | )
Weighted-average common shares used to compute basic and diluted net loss per share |  |  | 54,787,118 |  |  |  | 43,825,991 |  |  |  | 34,618,237 |
Net loss per share, basic and diluted |  | $ | (2.24 | ) |  | $ | (1.93 | ) |  | $ | (1.43 | )
The following outstanding potentially dilutive securities were excluded from the computation of diluted net loss per share for the periods presented because including them would have been antidilutive:
|  | At December 31, |
|  | 2020 |  |  | 2019 |  |  | 2018 |
Common stock options issued and outstanding |  |  | 9,892,697 |  |  |  | 4,738,004 |  |  |  | 1,458,079 |
Unvested restricted stock issued as part of collaboration agreement |  |  | 1,257,651 |  |  |  | 1,257,651 |  |  |  | - |
Unvested early exercised common stock options |  |  | 165,133 |  |  |  | 455,158 |  |  |  | 927,123 |
Unvested restricted stock units |  |  | 738,650 |  |  |  | - |  |  |  | - |
Employee Stock Purchase Plan shares |  |  | 18,219 |  |  |  | - |  |  |  | - |
Unvested restricted common stock |  |  | - |  |  |  | - |  |  |  | 289,352 |
Total |  |  | 12,072,350 |  |  |  | 6,450,813 |  |  |  | 2,674,554 |

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