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Liability for Sale of Future Royalties - Additional Information (Details) - BVF Partners L.P. - BVF Agreement - USD ($) | 1 Months Ended | 3 Months Ended | 12 Months Ended
--- | --- | --- | ---
Oct. 31, 2021 | Mar. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2022
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |
Payment to be made for discovery and development of compounds | $ 15,000,000 |  |  |
Cash received from counterparty |  | $ 5,000,000 | $ 5,000,000 |
Option to provide additional funding | 10,000,000 |  |  |
Liability for milestone payments and royalties |  | $ 10,700,000 |  |
Imputed effective rate of interest on unamortized portion of liability |  | 20.60% |  |
Non-cash interest expense |  | $ 400,000 |  |
Minimum |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |
Payment to be made for discovery and development of compounds | 15,000,000 |  |  |
Contingent payments upon achievement of certain clinical and regulatory milestones | 72,500,000 |  |  |
Maximum |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |
Contingent payments upon achievement of certain clinical and regulatory milestones | $ 160,000,000.0 |  |  |
Scenario Forecast |  |  |  |
Research and Development Arrangement, Contract to Perform for Others [Line Items] |  |  |  |
Cash received from counterparty |  |  |  | $ 5,000,000

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- Definition Cash received from collaborators during the current period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3536-108585 + Details
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