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Net Loss per Share - Summary of Outstanding Potentially Dilutive Securities Excluded from Computation of Diluted Net Loss per Share (Details) - shares | 3 Months Ended
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Mar. 31, 2022 | Mar. 31, 2021
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 14,225,764 | 14,706,123
Common Stock Options Issued and Outstanding |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 12,564,969 | 11,708,625
Restricted Stock Units Issued |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 1,558,381 | 1,532,162
Employee Stock Purchase Plan Shares |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share | 102,414 | 96,591
Unvested Early Exercised Common Stock Options |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share |  | 111,094
Unvested Restricted Common Stock Issued as Part of Collaboration Agreement |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |
Antidilutive securities excluded from computation of diluted net loss per share |  | 1,257,651

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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