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Fair Value Measurements - Additional Information (Details) - BVF Partners L.P. - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2023 | Mar. 31, 2023 | Sep. 30, 2022 | Sep. 30, 2022 | Dec. 31, 2022 | Dec. 31, 2021
BVF Agreement |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |
Non-refundable payments received |  |  |  |  | $ 15 | $ 15
Imputed effective rate of interest on unamortized portion of liability | 10.10% | 20.60% | 20.60% | 20.60% |  |
BVF Agreement | Maximum |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |
Contingent payments upon achievement of certain clinical and regulatory milestones |  |  |  |  |  | 73
Gilead Collaboration Agreement | Maximum |  |  |  |  |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |  |  |  |  |
Contingent payments upon achievement of certain clinical and regulatory milestones |  |  |  |  |  | $ 160

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