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Fair Value Measurements - Schedule of Assets and Liabilities Measured at Fair Value on Recurring Basis (Details) - Fair Value On Recurring Basis - USD ($) $ in Millions | Sep. 30, 2023 | Dec. 31, 2022
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Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | $ 950 | $ 1,138
Total liabilities measured at fair value | 19 | 17
Liability for sale of future royalties |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total liabilities measured at fair value | 19 | 17
Money market funds |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 110 | 169
U.S. treasury securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 245 | 314
Corporate securities and commercial paper |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 491 | 631
U.S. government agency obligations |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 96 |
U.S. government agency securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value |  | 20
Certificate of deposit |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 8 | 4
Level 1 |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 110 | 169
Total liabilities measured at fair value | 0 | 0
Level 1 | Liability for sale of future royalties |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total liabilities measured at fair value | 0 | 0
Level 1 | Money market funds |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 110 | 169
Level 1 | U.S. treasury securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Level 1 | Corporate securities and commercial paper |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Level 1 | U.S. government agency obligations |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 |
Level 1 | U.S. government agency securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value |  | 0
Level 1 | Certificate of deposit |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Level 2 |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 840 | 969
Total liabilities measured at fair value | 0 | 0
Level 2 | Liability for sale of future royalties |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total liabilities measured at fair value | 0 | 0
Level 2 | Money market funds |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Level 2 | U.S. treasury securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 245 | 314
Level 2 | Corporate securities and commercial paper |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 491 | 631
Level 2 | U.S. government agency obligations |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 96 |
Level 2 | U.S. government agency securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value |  | 20
Level 2 | Certificate of deposit |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 8 | 4
Level 3 |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Total liabilities measured at fair value | 19 | 17
Level 3 | Liability for sale of future royalties |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total liabilities measured at fair value | 19 | 17
Level 3 | Money market funds |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Level 3 | U.S. treasury securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Level 3 | Corporate securities and commercial paper |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 | 0
Level 3 | U.S. government agency obligations |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | 0 |
Level 3 | U.S. government agency securities |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value |  | 0
Level 3 | Certificate of deposit |  |
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] |  |
Total assets measured at fair value | $ 0 | $ 0

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