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Goodwill and Other Intangible Assets
6 Months Ended
Jun. 30, 2022
Goodwill and Intangible Assets Disclosure [Abstract]  
Goodwill and Other Intangible Assets Goodwill and Other Intangible Assets
The changes in the net carrying amount of goodwill for the six months ended June 30, 2022 are as follows:

Balance as of December 31, 2021$617,528 
Goodwill resulting from business acquisition140,338 
Foreign currency translation(1,113)
Balance as of June 30, 2022$756,753 
Assets and liabilities of acquired businesses are recorded at their estimated fair values as of the date of acquisition.  Goodwill represents costs in excess of fair values assigned to the underlying net assets of acquired businesses.  During the three months ended June 30, 2022, the Company acquired In2Bones Global, Inc. as further described in Note 4. Goodwill resulting from the acquisition amounted to $140.3 million and acquired intangible assets including distributor relationships and developed technology amounted to $63.9 million.
Other intangible assets consist of the following:

 June 30, 2022December 31, 2021
Weighted Average Amortization Period (Years)Gross
Carrying
Amount
Accumulated
Amortization
Gross
Carrying
Amount
Accumulated
Amortization
Intangible assets with definite lives:22
Customer and distributor relationships24$368,835 $(161,651)$342,452 $(152,934)
Sales representation, marketing and promotional rights25149,376 (63,000)149,376 (60,000)
Developed technology15143,904 (30,208)106,604 (26,495)
Patents and other intangible assets1477,191 (51,671)76,392 (50,890)
Intangible assets with indefinite lives:    
Trademarks and tradenames86,544 — 86,544 — 
$825,850 $(306,530)$761,368 $(290,319)

Customer and distributor relationships, trademarks and tradenames, developed technology and patents and other intangible assets primarily represent allocations of purchase price to identifiable intangible assets of acquired businesses. Sales representation, marketing and promotional rights represent intangible assets created under our agreement with Musculoskeletal Transplant Foundation (“MTF”).

Amortization expense related to intangible assets which are subject to amortization totaled $8.2 million for both the three months ended June 30, 2022 and 2021, and $16.2 million and $16.6 million in the six months ended June 30, 2022 and 2021, respectively, and is included as a reduction of revenue (for amortization related to our sales representation, marketing and promotional rights) and in selling and administrative expense (for all other intangible assets) in the consolidated condensed statements of comprehensive income (loss).
 
The estimated intangible asset amortization expense remaining for the year ending December 31, 2022 and for each of the five succeeding years is as follows:
 
Amortization included in expenseAmortization recorded as a reduction of revenueTotal
Remaining, 2022$14,731 $3,000 $17,731 
202328,715 6,000 34,715 
202428,427 6,000 34,427 
202528,846 6,000 34,846 
202628,502 6,000 34,502 
202729,207 6,000 35,207