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      </link:roleType>
    </xs:appinfo>
  </xs:annotation>
  <xs:element id="cnmd_SettlementOfConvertibleNotesHedgeTransactions" abstract="false" name="SettlementOfConvertibleNotesHedgeTransactions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_PaymentsForContingentConsideration" abstract="false" name="PaymentsForContingentConsideration" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_AmericasexcludingtheUnitedStatesMember" abstract="true" name="AmericasexcludingtheUnitedStatesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_OrthopedicSurgeryMember" abstract="true" name="OrthopedicSurgeryMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_GeneralSurgeryMember" abstract="true" name="GeneralSurgeryMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_RevenuesMember" abstract="true" name="RevenuesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_In2BonesGlobalIncMember" abstract="true" name="In2BonesGlobalIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_BiorezIncMember" abstract="true" name="BiorezIncMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_MeasurementInputRevenueVolatilityMember" abstract="true" name="MeasurementInputRevenueVolatilityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_BusinessAcquisitionContingentConsiderationAtFairValueRollForwardRollForward" abstract="true" name="BusinessAcquisitionContingentConsiderationAtFairValueRollForwardRollForward" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cnmd_BusinessAcquisitionContingentConsiderationPayment" abstract="false" name="BusinessAcquisitionContingentConsiderationPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_ScheduleOfFiniteLivedAndIndefiniteLivedAssetsTable" abstract="true" name="ScheduleOfFiniteLivedAndIndefiniteLivedAssetsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="cnmd_CustomerandDistributorRelationshipsMember" abstract="true" name="CustomerandDistributorRelationshipsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_SalesrepresentationmarketingandpromotionalrightsMember" abstract="true" name="SalesrepresentationmarketingandpromotionalrightsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_PatentsAndOtherIntangibleAssetsMember" abstract="true" name="PatentsAndOtherIntangibleAssetsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_ExpenseMember" abstract="true" name="ExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_ReductionofRevenueMember" abstract="true" name="ReductionofRevenueMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_ScheduleOfFiniteLivedAndIndefiniteLivedAssetsLineItems" abstract="true" name="ScheduleOfFiniteLivedAndIndefiniteLivedAssetsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="cnmd_AmendedAndRestatedSeniorCreditAgreementMember" abstract="true" name="AmendedAndRestatedSeniorCreditAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_A2250PercentConvertibleNotesDue2027Member" abstract="true" name="A2250PercentConvertibleNotesDue2027Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_A2.625PercentConvertibleNotesDue2024Member" abstract="true" name="A2.625PercentConvertibleNotesDue2024Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_IndexedTransactionTypeAxis" abstract="true" name="IndexedTransactionTypeAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="cnmd_IndexedTransactionTypeDomain" abstract="true" name="IndexedTransactionTypeDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_AlternateBaseRateSpreadNewYorkFederalReserveBankRateMember" abstract="true" name="AlternateBaseRateSpreadNewYorkFederalReserveBankRateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_AlternateBaseRateSpreadSecuredOvernightFinancingRateSOFRMember" abstract="true" name="AlternateBaseRateSpreadSecuredOvernightFinancingRateSOFRMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cnmd_TermSOFRInterestRate" abstract="false" name="TermSOFRInterestRate" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="cnmd_HedgeAndWarrantTransactionsNetCashPaid" abstract="false" name="HedgeAndWarrantTransactionsNetCashPaid" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_SalesforceAndCommissionExpense" abstract="false" name="SalesforceAndCommissionExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_DistributionExpense" abstract="false" name="DistributionExpense" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_ProductLiabilityContingencyInsuranceAggregateAnnualAmount" abstract="false" name="ProductLiabilityContingencyInsuranceAggregateAnnualAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_ProductLiabilityContingencyInsuranceAmountPerOccurrence" abstract="false" name="ProductLiabilityContingencyInsuranceAmountPerOccurrence" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cnmd_ToddGarnerMember" abstract="true" name="ToddGarnerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
