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Stockholders' Equity - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 9 Months Ended
May 26, 2023
May 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Mar. 31, 2021
Sep. 30, 2023
Sep. 30, 2022
May 09, 2023
Apr. 12, 2023
Class Of Stock [Line Items]                  
Proceeds from issuance of common stock     $ 162,000 $ 81,200   $ 0 $ 19,427    
Common stock, new shares issued     7,840,909 3,802,144          
Offering price     $ 22            
Number of pre funded warrants exercised for common stock               498,137 273,000
Incyte Collaboration Agreement and Share Purchase Agreement [Member]                  
Class Of Stock [Line Items]                  
Proceeds from issuance of common stock       $ 35,000          
Common stock, new shares issued       1,421,523          
Common stock issued at fair value       $ 24,800          
At The Market Equity Offering Sales Agreement [Member]                  
Class Of Stock [Line Items]                  
Proceeds from issuance of common stock $ 25,000                
Common stock, new shares issued           0      
Pre Funded Warrants [Member]                  
Class Of Stock [Line Items]                  
Warrants issued (in shares)       1,142,856          
Offering price       $ 17.4999          
Number of pre funded warrants exercised for common stock           285,714   498,142 272,996
Series Warrants [Member]                  
Class Of Stock [Line Items]                  
Offering price       $ 17.5          
Cowen and Company LLC [Member] | At The Market Equity Offering Sales Agreement [Member]                  
Class Of Stock [Line Items]                  
Proceeds from issuance of common stock   $ 200,000     $ 75,000