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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2024 | Mar. 31, 2023
CASH FLOWS FROM OPERATING ACTIVITIES: |  |
Net loss | $ (72,400) | $ (41,126)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 3 | 3
Accretion of investments | (3,821) | (3,967)
Non-cash operating lease expense | 244 | 110
Stock-based compensation | 8,899 | 6,238
Changes in operating assets and liabilities: |  |
Prepaid expenses and other assets | (2,854) | 2,899
Collaboration receivable (payable), net | 315 | 2,082
Other receivable | (6,073) | 0
Accounts payable | (1,152) | 3,707
Accrued expenses and other liabilities | (6,709) | (9,174)
Net cash used in operating activities | (83,548) | (39,228)
CASH FLOWS FROM INVESTING ACTIVITIES: |  |
Purchases of short and long-term investments | (167,385) | (61,585)
Proceeds from sales and maturities of short-term investments | 67,986 | 81,500
Net cash provided by (used in) investing activities | (99,399) | 19,915
CASH FLOWS FROM FINANCING ACTIVITIES: |  |
Proceeds from Employee Stock Purchase Plan | 309 | 196
Proceeds from stock option exercises | 1,859 | 2,278
Net cash provided by financing activities | 2,168 | 2,474
NET INCREASE (DECREASE) IN CASH, CASH EQUIVALENTS AND RESTRICTED CASH | (180,779) | (16,839)
CASH, CASH EQUIVALENTS AND RESTRICTED CASH—beginning of period | 295,611 | 74,471
CASH, CASH EQUIVALENTS AND RESTRICTED CASH —end of period | $ 114,832 | $ 57,632

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- Definition Amount of noncash expense for share-based payment arrangement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (a) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28 + Details
Name: | us-gaap_ShareBasedCompensation
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration