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Stockholders' Equity - Summary of Changes in Stockholders' Equity (Detail) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Class of Stock [Line Items]    
Beginning balance $ 554,196 $ 467,449
Stock-based compensation expense 8,899 6,238
Unrealized (loss) gain on short-term investments (974) 470
Employee withholdings ESPP 309 196
Proceeds from exercise of stock options 1,859 2,278
Net Income (Loss) (72,400) (41,126)
Ending balance 491,889 435,505
Common Stock [Member]    
Class of Stock [Line Items]    
Beginning balance $ 8 $ 7
Beginning balance, shares 84,826,632 68,111,385
Stock purchase under ESPP, shares 35,463 16,537
Vesting of RSU, shares 3,750 5,000
Prefunded warrants, exercise, shares   85,998
Proceeds from exercise of stock options, shares 113,841 276,506
Ending balance $ 8 $ 7
Ending balance, shares 84,979,686 68,495,426
Additional Paid-In Capital [Member]    
Class of Stock [Line Items]    
Beginning balance $ 1,456,370 $ 1,161,288
Stock-based compensation expense 8,899 6,238
Employee withholdings ESPP 309 196
Proceeds from exercise of stock options 1,859 2,278
Ending balance 1,467,437 1,170,000
Accumulated Other Comprehensive(Loss) / Income [Member]    
Class of Stock [Line Items]    
Beginning balance 218 (806)
Unrealized (loss) gain on short-term investments (974) 470
Ending balance (756) (336)
Accumulated Deficit [Member]    
Class of Stock [Line Items]    
Beginning balance (902,400) (693,040)
Net Income (Loss) (72,400) (41,126)
Ending balance $ (974,800) $ (734,166)