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Segment Reporting (Tables) | 6 Months Ended
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Jun. 30, 2026
Segment Reporting [Abstract] |
Schedule of Operating Financial Results | The following table provides the operating financial results of our biopharmaceutical cancer therapeutics segment:
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2026 |  |  | 2025 |  |  | 2026 |  |  | 2025 |
June 30, 2026 |  |  |  |  |  |  |  |  |  |  |  |
Total Revenue |  | $ | 72,788 |  |  | $ | 37,958 |  |  | $ | 137,652 |  |  | $ | 57,753 |
Less: Significant and other segment expenses |  |  |  |  |  |  |  |  |  |  |  |
Cost of product sales |  |  | 3,208 |  |  |  | 1,279 |  |  |  | 5,841 |  |  |  | 2,164 |
Research and development expenses |  |  |  |  |  |  |  |  |  |  |  |
Revumenib-related costs |  |  | 35,493 |  |  |  | 28,155 |  |  |  | 61,218 |  |  |  | 48,960 |
Axatilimab-related costs |  |  | 8,682 |  |  |  | 9,053 |  |  |  | 18,315 |  |  |  | 28,764 |
Other R&D programs |  |  | 1,043 |  |  |  | 1,826 |  |  |  | 1,205 |  |  |  | 2,747 |
Personnel cost and other expenses |  |  | 18,308 |  |  |  | 18,997 |  |  |  | 37,606 |  |  |  | 35,528 |
General and administrative expenses |  |  |  |  |  |  |  |  |  |  |  |
Commercial-related expenses |  |  | 9,869 |  |  |  | 9,914 |  |  |  | 17,590 |  |  |  | 20,739 |
Personnel cost and other expenses |  |  | 16,298 |  |  |  | 19,307 |  |  |  | 32,999 |  |  |  | 38,389 |
Other SG&A expenses |  |  | 5,868 |  |  |  | 4,993 |  |  |  | 11,008 |  |  |  | 9,405 |
Stock-based compensation |  |  | 14,014 |  |  |  | 13,787 |  |  |  | 26,067 |  |  |  | 24,167 |
Royalty interest expense |  |  | 12,119 |  |  |  | 7,854 |  |  |  | 23,965 |  |  |  | 15,903 |
Convertible note interest expense |  |  | 555 |  |  |  | — |  |  |  | 555 |  |  |  | — |
Interest expense (income), net |  |  | (3,744 | ) |  |  | (5,946 | ) |  |  | (7,305 | ) |  |  | (13,127 | )
Other expense, net |  |  | 438 |  |  |  | 586 |  |  |  | 624 |  |  |  | 807 |
Segment net loss |  | $ | (49,363 | ) |  | $ | (71,847 | ) |  | $ | (92,036 | ) |  | $ | (156,693 | )

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- Definition Tabular disclosure of segment reporting. Includes, but is not limited to, reconciliation of reportable segment amount to corresponding consolidated total. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 34 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-34 Reference 3: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 32 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-32 Reference 4: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 Reference 5: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26C -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26C Reference 6: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26B -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26B Reference 7: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 26A -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-26A Reference 8: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 9: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 10: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 15 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-15 + Details
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