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CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2026
Jun. 30, 2025
Jun. 30, 2026
Jun. 30, 2025
Revenue:        
Total revenues $ 72,788 $ 37,958 $ 137,652 $ 57,753
Operating expenses:        
Cost of Product Sales 3,208 1,279 5,841 2,164
Research and development 68,036 62,227 126,881 123,863
Selling, general and administrative 41,539 43,805 79,127 84,836
Total operating expenses 112,783 107,311 211,849 210,863
Loss from operations (39,995) (69,353) (74,197) (153,110)
Other income (expense), net:        
Royalty interest expense (12,119) (7,854) (23,965) (15,903)
Convertible note interest expense (555) 0 (555) 0
Other interest expense (2) (4) (2) (6)
Interest income 3,746 5,950 7,307 13,133
Other expense (438) (586) (624) (807)
Total other (expense) income, net (9,368) (2,494) (17,839) (3,583)
Net loss (49,363) (71,847) (92,036) (156,693)
Other Comprehensive loss:        
Unrealized (loss) gain on marketable securities (151) (242) (592) 122
Other Comprehensive loss $ (49,514) $ (72,089) $ (92,628) $ (156,571)
Basic loss per share attributable to common stockholders $ (0.55) $ (0.83) $ (1.04) $ (1.82)
Diluted loss per share attributable to common stockholders $ (0.55) $ (0.83) $ (1.04) $ (1.82)
Weighted-average number of common shares used to compute net loss per share attributable to common stockholders —basic 88,991,317 86,337,237 88,625,508 86,255,020
Weighted-average number of common shares used to compute net loss per share attributable to common stockholders—diluted 88,991,317 86,337,237 88,625,508 86,255,020
Product        
Revenue:        
Total revenues $ 54,700 $ 28,600 $ 103,623 $ 48,642
Collaboration revenue        
Revenue:        
Total revenues $ 18,088 $ 9,358 $ 34,029 $ 9,111