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Income Taxes (Tax Rates) (Details) | 12 Months Ended
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Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Statutory federal tax rate | (34.00%) | (34.00%) | (34.00%)
State income taxes, net of federal benefit | (3.00%) | (3.00%) | (3.00%)
Research and development and other tax credits | (3.00%) | (2.00%) | (7.00%)
Expiration of net operating losses | 0.00% | 0.00% | 0.00%
Release of FIN 48 liability | (2.00%) | 0.00% | 0.00%
Other | 1.00% | 2.00% | 3.00%
Change in valuation allowance | 41.00% | 37.00% | 41.00%
Effective tax rate | 0.00% | 0.00% | 0.00%

X
- Definition Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to release of FIN 48 liability. + References No definition available. + Details
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- Definition Percentage of domestic federal statutory tax rate applicable to pretax income (loss). + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32687-109319 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB TOPIC 6.I) -URI http://asc.fasb.org/extlink&oid=34349781&loc=d3e330036-122817 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 13 -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32698-109319 + Details
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