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Other Financial Information | 12 Months Ended
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Dec. 31, 2015
Other Financial Information [Abstract] |
Other Financial Information | Note 9 – Other Financial Information Prepaid Expenses and Other Current Assets Prepaid expenses and other current assets consist of the following at December 31 (in thousands):
|  | 2015 |  | 2014 |
Laboratory supplies |  | $ | 12,968 |  | $ | 7,564 |
Other prepaid expenses and other current assets |  |  | 6,349 |  |  | 1,631 |
Prepaid expenses and other current assets |  | $ | 19,317 |  | $ | 9,195 |
Property and Equipment, net Property and equipment is comprised of the following at December 31 (in thousands):
|  | 2015 |  | 2014 |
Machinery and equipment |  | $ | 26,461 |  | $ | 16,712 |
Leasehold improvements |  |  | 12,440 |  |  | 8,843 |
Computer software and hardware |  |  | 3,091 |  |  | 1,733 |
Construction in progress |  |  | 6,167 |  |  | 3,719 |
|  |  | 48,159 |  |  | 31,007 |
Less — accumulated depreciation and amortization |  |  | (15,817) |  |  | (11,270) |
Property and equipment, net |  | $ | 32,342 |  | $ | 19,737 |
Depreciation and amortization expense was approximately $6.0 million, $4.4 million and $2.6 million for the years ended December 31, 2015, 2014 and 2013, respectively. Machinery and equipment included $0.4 million of equipment acquired under a capital lease with accumulated depreciation of $0.3 million and $0.2 million as of December 31, 2015 and 2014, respectively. Accrued Expenses Accrued expenses consist of the following at December 31 (in thousands):
|  | 2015 |  | 2014 |
Employee benefits and compensation |  | $ | 11,255 |  | $ | 8,597 |
Research and development accruals |  |  | 13,814 |  |  | 9,826 |
Other accrued expenses |  |  | 1,665 |  |  | 974 |
Accrued expenses |  | $ | 26,734 |  | $ | 19,397 |

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