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Commitments and Contingencies (Narrative) (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Sep. 30, 2015
Tenant Improvement Allowance $ 3.9      
Proceeds from Improvement Allowance 1.4      
Rent expense 4.2 $ 3.6 $ 3.4  
Purchase obligation, minimum amount $ 7.5      
Accrued milestone payment associated with the first Phase 3 clinical trial       $ 3.0
Notice period required for termination of license agreement 90 days      
Aggregate amount of payments made under license agreement $ 7.3      
Maximum [Member]        
Increase In License Maintenance Fees 0.3      
Increase In Milestone Payment 15.0      
Minimum [Member]        
Increase In License Maintenance Fees 0.2      
Increase In Milestone Payment 14.0      
Cadila [Member]        
Purchase obligation, minimum amount 7.5      
Purchase Obligation Services Received $ 2.2