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Other Financial Information | 12 Months Ended
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Dec. 31, 2016
Other Financial Information [Abstract] |
Other Financial Information | Note 8 – Other Financial Information Prepaid Expenses and Other Current Assets Prepaid expenses and other current assets consist of the following at December 31 (in thousands):
|  | 2016 |  | 2015 |
Laboratory supplies |  | $ | 15,736 |  | $ | 12,968 |
Other prepaid expenses and other current assets |  |  | 6,068 |  |  | 6,349 |
Prepaid expenses and other current assets |  | $ | 21,804 |  | $ | 19,317 |
Property and Equipment, net Property and equipment is comprised of the following at December 31 (in thousands):
|  | 2016 |  | 2015 |
Machinery and equipment |  | $ | 32,596 |  | $ | 26,461 |
Leasehold improvements |  |  | 22,642 |  |  | 12,440 |
Computer software and hardware |  |  | 4,285 |  |  | 3,091 |
Construction in progress |  |  | 2,938 |  |  | 6,167 |
|  |  | 62,461 |  |  | 48,159 |
Less — accumulated depreciation and amortization |  |  | (22,277) |  |  | (15,817) |
Property and equipment, net |  | $ | 40,184 |  | $ | 32,342 |
Depreciation and amortization expense was approximately $8.5 million, $6.0 million and $4.4 million for the years ended December 31, 2016, 2015 and 2014, respectively. Accrued Expenses Accrued expenses consist of the following at December 31 (in thousands):
|  | 2016 |  | 2015 |
Employee benefits and compensation |  | $ | 7,300 |  | $ | 11,255 |
Research and development accruals |  |  | 15,744 |  |  | 13,814 |
Other accrued expenses |  |  | 1,464 |  |  | 1,665 |
Accrued expenses |  | $ | 24,508 |  | $ | 26,734 |

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