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Other Financial Information (Tables) | 12 Months Ended
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Dec. 31, 2016
Other Financial Information [Abstract] |
Prepaid Expenses and Other Current Assets | Prepaid expenses and other current assets consist of the following at December 31 (in thousands):
|  | 2016 |  | 2015 |
Laboratory supplies |  | $ | 15,736 |  | $ | 12,968 |
Other prepaid expenses and other current assets |  |  | 6,068 |  |  | 6,349 |
Prepaid expenses and other current assets |  | $ | 21,804 |  | $ | 19,317 |
Property and Equipment, Net | Property and equipment is comprised of the following at December 31 (in thousands):
|  | 2016 |  | 2015 |
Machinery and equipment |  | $ | 32,596 |  | $ | 26,461 |
Leasehold improvements |  |  | 22,642 |  |  | 12,440 |
Computer software and hardware |  |  | 4,285 |  |  | 3,091 |
Construction in progress |  |  | 2,938 |  |  | 6,167 |
|  |  | 62,461 |  |  | 48,159 |
Less — accumulated depreciation and amortization |  |  | (22,277) |  |  | (15,817) |
Property and equipment, net |  | $ | 40,184 |  | $ | 32,342 |
Accrued Expenses | Accrued expenses consist of the following at December 31 (in thousands):
|  | 2016 |  | 2015 |
Employee benefits and compensation |  | $ | 7,300 |  | $ | 11,255 |
Research and development accruals |  |  | 15,744 |  |  | 13,814 |
Other accrued expenses |  |  | 1,464 |  |  | 1,665 |
Accrued expenses |  | $ | 24,508 |  | $ | 26,734 |

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- Definition Tabular disclosure of the amounts paid in advance for capitalized costs that will be expensed with the passage of time or the occurrence of a triggering event, and will be charged against earnings within one year or the normal operating cycle, if longer; the aggregate carrying amount of current assets, not separately presented elsewhere in the balance sheet; and other deferred costs. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.17) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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- Definition Tabular disclosure of physical assets used in the normal conduct of business and not intended for resale. Includes, but is not limited to, balances by class of assets, depreciation and depletion expense and method used, including composite depreciation, and accumulated deprecation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(13)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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