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v3.19.1

CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2019 | Mar. 31, 2018
Operating Activities: |  |
Net loss | $ (43,218) | $ (46,352)
Reconciliation of net loss to net cash used in operating activities: |  |
Depreciation and amortization | 1,939 | 2,079
Loss (Gain) on disposal of property and equipment | 88 | (47)
Non-cash impact of lease termination | 0 | (4,381)
Amortization of debt issuance costs | 356 | 356
Non-cash stock-based compensation | 5,558 | 5,245
Other | (14) | (435)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other assets | (296) | 0
Accounts payable and accrued expenses | (11,853) | (13,293)
Deferred revenue | (3,167) | (9,247)
Net cash used in operating activities | (50,607) | (66,075)
Investing Activities: |  |
Capital expenditures | (805) | (150)
Proceeds from maturities of marketable securities | 22,000 | 22,721
Purchases of marketable securities | (2,484) | (1,984)
Net cash provided by investing activities | 18,711 | 20,587
Financing Activities: |  |
Net proceeds from sales of common stock | 55,239 | 42,599
Proceeds from the exercise of stock options and employee stock purchases | 942 | 1,325
Net cash provided by financing activities | 56,181 | 43,924
Effect of exchange rate on cash, cash equivalents and restricted cash | (45) | (26)
Net increase (decrease) in cash, cash equivalents and restricted cash | 24,240 | (1,590)
Cash, cash equivalents and restricted cash at beginning of period | 81,959 | 135,431
Cash, cash equivalents and restricted cash at end of period | 106,199 | 133,841
Supplemental disclosure of non-cash activities: |  |
Property and equipment purchases included in accounts payable and accrued expenses | 194 | 62
Supplemental disclosure of cash flow information: |  |
Cash payments of interest | $ 6,094 | $ 6,094

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