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Intangible Assets and Goodwill (Tables) | 6 Months Ended
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Jun. 30, 2022
Goodwill and Intangible Assets Disclosure [Abstract] |
Schedule of identifiable intangible assets | Purchased intangible assets consisted of the following (in thousands):
| June 30, 2022 |  | December 31, 2021
| Gross Carrying Amount |  | Accumulated Amortization |  | Intangible Assets, Net |  | Gross Carrying Amount |  | Accumulated Amortization |  | Intangible Assets, Net
Finite-lived intangible assets: |  |  |  |  |  |  |  |  |  |  |
Proprietary adjuvant technology | $ | 7,278 |  |  | $ | (3,245) |  |  | $ | 4,033 |  |  | $ | 8,239 |  |  | $ | (3,469) |  |  | $ | 4,770 |
Collaboration agreements | 3,286 |  |  | (3,286) |  |  | — |  |  | 3,722 |  |  | (3,722) |  |  | — |
Total identifiable intangible assets | $ | 10,564 |  |  | $ | (6,531) |  |  | $ | 4,033 |  |  | $ | 11,961 |  |  | $ | (7,191) |  |  | $ | 4,770 |
Schedule of estimated amortization expense | Estimated amortization expense for existing intangible assets for the remainder of 2022 and for each of the five succeeding years ending December 31 will be as follows (in thousands):
Year |  | Amount
2022 (remainder) |  | $ | 182 |
2023 |  | 364 |
2024 |  | 364 |
2025 |  | 364 |
2026 |  | 364 |
2027 |  | 364 |
Schedule of goodwill | The change in the carrying amounts of goodwill for the six months ended June 30, 2022 was as follows (in thousands):
| Amount
Balance at December 31, 2021 | $ | 131,479 |
Currency translation adjustments | (8,012) |
Balance at June 30, 2022 | $ | 123,467 |

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