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Intangible Assets and Goodwill
 6 Months Ended
Jun. 30, 2022
Goodwill and Intangible Assets Disclosure [Abstract]  
Intangible Assets and Goodwill Intangible Assets and Goodwill
Identifiable Intangible Assets
Purchased intangible assets consisted of the following (in thousands):
June 30, 2022December 31, 2021
Gross
Carrying
Amount		Accumulated 
Amortization		Intangible
Assets, Net		Gross
Carrying
Amount		Accumulated 
Amortization		Intangible
Assets, Net
Finite-lived intangible assets:
Proprietary adjuvant technology$7,278 $(3,245)$4,033 $8,239 $(3,469)$4,770 
Collaboration agreements3,286 (3,286)— 3,722 (3,722)— 
Total identifiable intangible assets$10,564 $(6,531)$4,033 $11,961 $(7,191)$4,770 
Amortization expense for the six months ended June 30, 2022 and 2021 was $0.2 million. Estimated amortization expense for existing intangible assets for the remainder of 2022 and for each of the five succeeding years ending December 31 will be as follows (in thousands):
YearAmount
2022 (remainder)$182 
2023364 
2024364 
2025364 
2026364 
2027364 
Goodwill
The change in the carrying amounts of goodwill for the six months ended June 30, 2022 was as follows (in thousands):
Amount
Balance at December 31, 2021$131,479 
Currency translation adjustments(8,012)
Balance at June 30, 2022$123,467