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Stock-Based Compensation - Schedule of Assumptions Used in Estimation of Fair Value of Stock (Details) - $ / shares | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Options |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |
Black-Scholes fair value (in usd per share) | $ 55.32 | $ 158.02 | $ 80.48
Risk-free interest rate, minimum | 1.40% | 0.50% | 0.20%
Risk-free interest rate, maximum | 4.30% | 1.30% | 1.50%
Dividend yield | 0.00% | 0.00% | 0.00%
Volatility, minimum | 120.50% | 124.70% | 116.00%
Volatility, maximum | 140.10% | 142.00% | 152.20%
Options | Minimum |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |
Expected term (in years) | 4 years | 4 years 1 month 6 days | 3 years 10 months 24 days
Options | Maximum |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |
Expected term (in years) | 6 years 3 months 18 days | 6 years 1 month 6 days | 7 years 7 months 6 days
ESPP |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |
Risk-free interest rate, minimum | 0.60% | 0.10% | 0.20%
Risk-free interest rate, maximum | 3.30% | 0.20% | 2.60%
Dividend yield | 0.00% | 0.00% | 0.00%
Volatility, minimum | 103.00% | 114.90% | 66.60%
Volatility, maximum | 142.90% | 159.40% | 189.70%
ESPP | Minimum |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |
Black-Scholes fair value (in usd per share) | $ 23.59 | $ 83.47 | $ 2.57
Expected term (in years) | 6 months | 6 months | 6 months
ESPP | Maximum |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |
Black-Scholes fair value (in usd per share) | $ 79.74 | $ 238.85 | $ 92.67
Expected term (in years) | 2 years | 2 years | 2 years

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- Definition The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iii) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition The estimated measure of the maximum percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References No definition available. + Details
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- Definition The estimated measure of the minimum percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References No definition available. + Details
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- Definition The maximum risk-free interest rate assumption that is used in valuing an option on its own shares. + References No definition available. + Details
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- Definition The minimum risk-free interest rate assumption that is used in valuing an option on its own shares. + References No definition available. + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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- Definition The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d)(1) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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- Definition Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(i) -URI https://asc.fasb.org/extlink&oid=128089324&loc=d3e5070-113901 + Details
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