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Revenue - Additional Information (Details)
$ in Thousands
 1 Months Ended 12 Months Ended
Jan. 31, 2023
dose
Jul. 31, 2020
USD ($)
dose
Jun. 30, 2020
USD ($)
dose
May 31, 2020
USD ($)
Dec. 31, 2022
USD ($)
dose
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Nov. 30, 2022
dose
Nov. 18, 2022
dose
Jul. 31, 2022
USD ($)
dose
Mar. 31, 2022
USD ($)
Sep. 30, 2021
dose
Oct. 22, 2020
dose
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Billed contracts receivable         $ 53,800 $ 419,700              
Unbilled contracts receivable         28,600 35,300              
Deferred revenue         549,551 1,595,472 $ 273,228            
Purchase agreement, number of vaccine doses | dose                         60,000,000
Collaboration agreement upfront payment amount         819,000                
Total revenue         1,981,872 1,146,290 475,598            
Sales-Based Royalties                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Total revenue         $ 9,000 178,600              
Amended and Restated UK Supply Agreement | Minimum                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose                   1,000,000      
Amended and Restated UK Supply Agreement | Maximum                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose               7,500,000   15,000,000      
Gavi Advance Purchase Agreement SIIPL                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose         1,100,000,000                
Deferred revenue           350,000              
Remaining performance obligation, variable consideration amount                     $ 350,000    
Gavi Advance Purchase Agreement- COVAX Facility                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose                 350,000,000        
Purchase agreement, number of vaccine doses | dose                 2,000,000        
Collaboration agreement upfront payment amount         $ 697,400                
Joint Committee on Vaccination and Immunization (JCVI)                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose                   44,000,000      
Deferred revenue         112,500                
Collaboration agreement upfront payment amount         $ 112,500         $ 225,000      
European Commissions ("EC")                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose         100,000,000                
Purchase agreement, number of vaccine doses | dose         63,000,000                
Additional purchase option, number of doses | dose         200,000,000                
Number of doses, cancelled | dose         7,000,000                
European Commissions ("EC") | Subsequent Event                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses | dose 20,000,000                        
European Commissions ("EC") | Minimum                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose         20,000,000                
European Commissions ("EC") | Maximum                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose         100,000,000                
USG Agreement                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Purchase agreement, number of vaccine doses | dose                   3,000,000      
Number of doses | dose   100,000,000                      
Research and development arrangement, contract ceiling   $ 1,800,000                      
USG Agreement | Government Contract                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Revenue from contract with customer   $ 1,750,000     $ 1,400,000                
Research and development arrangement, contract to perform for others, contract remaining         416,000                
DoD Contract                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Purchase agreement, number of vaccine doses | dose                   200,000      
Additional purchase option, number of doses | dose                   9,800,000      
Number of doses | dose     10,000,000                    
Performance obligation, customer status, period     5 years                    
DoD Contract | Government Contract                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Revenue from contract with customer     $ 45,700                    
Coalition for Epidemic Preparedness Innovations ("CEPI")                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Contract to perform for others funding       $ 399,500                  
Contract to perform for others grant       257,000                  
Contract to perform for others forgivable no interest term loans       $ 142,500                  
CEPI Grant Funding                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Revenue from contract with customer         358,600 $ 358,600              
Takeda Arrangement                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Number of doses to be distributed | dose                       150,000,000  
Milestone payment recognized         20,000   $ 20,000            
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2023-01-01                          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                          
Remaining performance obligation to be satisfied         $ 3,000,000                
Remaining performance obligation, expected timing of satisfaction, period         1 year