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Income Taxes - Significant Components of the Company's Deferred Tax Assets (Detail) - USD ($) $ in Thousands | Dec. 31, 2016 | Dec. 31, 2015
--- | --- | ---
Deferred Tax Assets, Net [Abstract] |  |
Net operating loss carryforwards | $ 68,639 | $ 30,572
Research credits | 2,643 | 1,919
Stock awards | 2,583 | 1,011
Other | 1,558 | 571
Gross deferred tax assets | 75,423 | 34,073
Valuation allowance | (74,520) | (33,845)
Total deferred tax assets | 903 | 228
Deferred tax liabilities | (903) | (228)
Net deferred tax assets | $ 0 | $ 0

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