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Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($) $ in Thousands | Total | IPO [Member] | Private Placement [Member] | Public Offering [Member] | Private Investment in Public Equity (PIPE) [Member] | Convertible Preferred Stock [Member] | Common Stock [Member] | Common Stock [Member] Restricted Stock Units (RSUs) [Member] | Common Stock [Member] IPO [Member] | Common Stock [Member] Private Placement [Member] | Common Stock [Member] Public Offering [Member] | Common Stock [Member] Private Investment in Public Equity (PIPE) [Member] | Additional Paid-in Capital [Member] | Additional Paid-in Capital [Member] IPO [Member] | Additional Paid-in Capital [Member] Private Placement [Member] | Additional Paid-in Capital [Member] Public Offering [Member] | Additional Paid-in Capital [Member] Private Investment in Public Equity (PIPE) [Member] | Accumulated Deficit [Member] | Other Comprehensive Income (Loss) [Member]
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Balance, amount at Dec. 31, 2013 |  |  |  |  |  | $ 56,155 |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock, value |  | $ 61,241 |  |  |  |  |  |  | $ 1 |  |  |  |  | $ 61,240 |  |  |  |  |
Balance, amount at Dec. 31, 2013 | $ (63,479) |  |  |  |  |  |  |  |  |  |  |  | $ 5,174 |  |  |  |  | $ (68,653) |
Issuance of common stock, shares |  |  |  |  |  |  |  |  | 4,928,900 |  |  |  |  |  |  |  |  |  |
Balance, shares at Dec. 31, 2013 |  |  |  |  |  | 11,517,222 |  |  |  |  |  |  |  |  |  |  |  |  |
Balance, shares at Dec. 31, 2013 |  |  |  |  |  |  | 1,225,481 |  |  |  |  |  |  |  |  |  |  |  |
Conversion of convertible preferred stock to common stock in connection with initial public offering, amount | 56,155 |  |  |  |  | $ (56,155) | $ 1 |  |  |  |  |  | 56,154 |  |  |  |  |  |
Conversion of convertible preferred stock to common stock in connection with initial public offering, shares |  |  |  |  |  | (11,517,222) | 11,517,222 |  |  |  |  |  |  |  |  |  |  |  |
Net exercise and conversion of preferred stock warrants to common stock in connection with initial public offering, amount | 8,049 |  |  |  |  |  |  |  |  |  |  |  | 8,049 |  |  |  |  |  |
Net exercise and conversion of preferred stock warrants to common stock in connection with initial public offering, shares |  |  |  |  |  |  | 571,244 |  |  |  |  |  |  |  |  |  |  |  |
Exercise of stock options and vesting of early exercised stock options, net of repurchases, amount | $ 238 |  |  |  |  |  |  |  |  |  |  |  | 238 |  |  |  |  |  |
Exercise of stock options and vesting of early exercised stock options, net of repurchases, shares | 336,398 |  |  |  |  |  | 336,398 |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock for services, amount | $ 208 |  |  |  |  |  |  |  |  |  |  |  | 208 |  |  |  |  |  |
Issuance of common stock for services, shares | 10,000 |  |  |  |  |  | 10,000 |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation | $ 1,484 |  |  |  |  |  |  |  |  |  |  |  | 1,484 |  |  |  |  |  |
Net loss | (3,214) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (3,214) |
Balance, amount at Dec. 31, 2014 | 60,682 |  |  |  |  |  | $ 2 |  |  |  |  |  | 132,547 |  |  |  |  | (71,867) |
Balance, shares at Dec. 31, 2014 |  |  |  |  |  |  | 18,589,245 |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock, value |  |  | $ 74,323 |  |  |  |  |  |  | $ 1 |  |  |  |  | $ 74,322 |  |  |  |
Issuance of common stock, shares |  |  |  |  |  |  |  |  |  | 7,242,992 |  |  |  |  |  |  |  |  |
Issuance of common stock under employee stock purchase plan ,amount | 548 |  |  |  |  |  |  |  |  |  |  |  | 548 |  |  |  |  |  |
Issuance of common stock under employee stock purchase plan , shares |  |  |  |  |  |  | 41,580 |  |  |  |  |  |  |  |  |  |  |  |
Exercise of stock options and vesting of early exercised stock options, net of repurchases, amount | $ 111 |  |  |  |  |  |  |  |  |  |  |  | 111 |  |  |  |  |  |
Exercise of stock options and vesting of early exercised stock options, net of repurchases, shares | 77,784 |  |  |  |  |  | 77,784 |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock for services, amount | $ 194 |  |  |  |  |  |  |  |  |  |  |  | 194 |  |  |  |  |  |
Issuance of common stock for services, shares | 13,285 |  |  |  |  |  | 13,285 |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation | $ 2,634 |  |  |  |  |  |  |  |  |  |  |  | 2,634 |  |  |  |  |  |
Other | 30 |  |  |  |  |  |  |  |  |  |  |  | 30 |  |  |  |  |  |
Net loss | (29,621) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (29,621) |
Balance, amount at Dec. 31, 2015 | 108,901 |  |  |  |  |  | $ 3 |  |  |  |  |  | 210,386 |  |  |  |  | (101,488) |
Balance, shares at Dec. 31, 2015 |  |  |  |  |  |  | 25,964,886 |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock, value |  |  |  | $ 80,837 | $ 109,736 |  |  |  |  |  | $ 1 | $ 1 |  |  |  | $ 80,836 | $ 109,735 |  |
Issuance of common stock, shares |  |  |  |  |  |  |  | 5,000 |  |  | 8,625,000 | 12,600,230 |  |  |  |  |  |  |
Issuance of common stock under employee stock purchase plan ,amount | $ 576 |  |  |  |  |  |  |  |  |  |  |  | 576 |  |  |  |  |  |
Balance, shares at Dec. 31, 2015 | 25,964,886 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock under employee stock purchase plan , shares |  |  |  |  |  |  | 69,054 |  |  |  |  |  |  |  |  |  |  |  |
Exercise of stock options and vesting of early exercised stock options, net of repurchases, amount | $ 55 |  |  |  |  |  |  |  |  |  |  |  | 55 |  |  |  |  |  |
Exercise of stock options and vesting of early exercised stock options, net of repurchases, shares | 25,134 |  |  |  |  |  | 25,134 |  |  |  |  |  |  |  |  |  |  |  |
Issuance of common stock for services, amount | $ 187 |  |  |  |  |  |  |  |  |  |  |  | 187 |  |  |  |  |  |
Issuance of common stock for services, shares | 20,118 |  |  |  |  |  | 20,118 |  |  |  |  |  |  |  |  |  |  |  |
Stock-based compensation | $ 5,317 |  |  |  |  |  |  |  |  |  |  |  | 5,317 |  |  |  |  |  |
Other comprehensive loss | (71) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ (71)
Net loss | (112,387) |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | (112,387) |
Balance, amount at Dec. 31, 2016 | $ 193,151 |  |  |  |  |  | $ 5 |  |  |  |  |  | $ 407,092 |  |  |  |  | $ (213,875) | $ (71)
Balance, shares at Dec. 31, 2016 |  |  |  |  |  |  | 47,309,422 |  |  |  |  |  |  |  |  |  |  |  |

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- Definition Total of all stockholders' equity (deficit) items, net of receivables from officers, directors, owners, and affiliates of the entity which are attributable to the parent. The amount of the economic entity's stockholders' equity attributable to the parent excludes the amount of stockholders' equity which is allocable to that ownership interest in subsidiary equity which is not attributable to the parent (noncontrolling interest, minority interest). This excludes temporary equity and is sometimes called permanent equity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(30)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 310 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SAB Topic 4.E) -URI http://asc.fasb.org/extlink&oid=27010918&loc=d3e74512-122707 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(31)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(29)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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- Definition Carrying amount, attributable to parent and noncontrolling interests, of an entity's issued and outstanding stock which is not included within permanent equity. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable. Includes any type of security that is redeemable at a fixed or determinable price or on a fixed or determinable date or dates, is redeemable at the option of the holder, or has conditions for redemption which are not solely within the control of the issuer. Includes stock with a put option held by an ESOP and stock redeemable by a holder only in the event of a change in control of the issuer. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.27(b)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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- Definition The number of securities classified as temporary equity that have been issued and are held by the entity's shareholders. Securities outstanding equals securities issued minus securities held in treasury. Temporary equity is a security with redemption features that are outside the control of the issuer, is not classified as an asset or liability in conformity with GAAP, and is not mandatorily redeemable. Includes any type of security that is redeemable at a fixed or determinable price or on a fixed or determinable date or dates, is redeemable at the option of the holder, or has conditions for redemption which are not solely within the control of the issuer. If convertible, the issuer does not control the actions or events necessary to issue the maximum number of shares that could be required to be delivered under the conversion option if the holder exercises the option to convert the stock to another class of equity. If the security is a warrant or a rights issue, the warrant or rights issue is considered to be temporary equity if the issuer cannot demonstrate that it would be able to deliver upon the exercise of the option by the holder in all cases. Includes stock with put option held by ESOP and stock redeemable by holder only in the event of a change in control of the issuer. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(27)(b)) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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