Consolidated Statements of Operations - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Revenue:
Licensing revenue		$ 21,611	$ 18,394
Collaborative development revenue		2,415	13,229
Total revenue		24,026	31,623
Operating expenses:
Research and development	$ 94,161	39,885	25,900
General and administrative	18,734	13,530	7,287
Total operating expenses	112,895	53,415	33,187
Loss from operations	(112,895)	(29,389)	(1,564)
Other income (expense), net	508	(261)	10
Change in fair value of preferred stock warrant liability			(1,593)
Loss before provision for income taxes	(112,387)	(29,650)	(3,147)
Benefit from (Provision for) income taxes		29	(67)
Net loss	$ (112,387)	$ (29,621)	$ (3,214)
Net loss per common share, basic and diluted	$ (2.80)	$ (1.29)	$ (0.31)
Weighted-average number of common shares used in net loss per share, basic and diluted	40,118,522	22,892,640	10,248,337

The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

No definition available.