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Equity Incentive Plans - Summary of Weighted Average Assumptions to Estimate Fair value of Stock Option Awards and Employee Stock Purchase Plan (Detail)
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term ( years) 5 years 11 months 27 days 5 years 10 months 21 days 5 years 11 months 19 days
Volatility 77.00% 75.00% 94.00%
Risk-free interest rate 1.62% 1.64% 1.79%
Dividend yield 0.00% 0.00% 0.00%
2014 Employee Stock Purchase Plan [Member]      
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]      
Expected term ( years) 6 months 6 months  
Volatility 76.00% 97.00%  
Risk-free interest rate 0.48% 0.16%  
Dividend yield 0.00% 0.00%