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Net Loss per Share - Calculation of Anti-dilutive Potentially Dilutive Securities Not Included in Diluted Per Share (Detail) - shares
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, shares 4,730,213 1,544,744 1,007,724
Options to Purchase Common Stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, shares 2,557,314 1,244,442 1,007,724
Warrants to Purchase Common Stock [Member]      
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]      
Antidilutive securities excluded from computation of earnings per share, shares 2,172,899 300,302