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Consolidated Statements of Convertible Preferred Stock and Stockholders' Equity (Deficit) - USD ($)
$ in Thousands
Total
IPO [Member]
Private Placement [Member]
Public Offering [Member]
Private Investment in Public Equity (PIPE) [Member]
Convertible Preferred Stock [Member]
Common Stock [Member]
Common Stock [Member]
Restricted Stock Units (RSUs) [Member]
Common Stock [Member]
IPO [Member]
Common Stock [Member]
Private Placement [Member]
Common Stock [Member]
Public Offering [Member]
Common Stock [Member]
Private Investment in Public Equity (PIPE) [Member]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
IPO [Member]
Additional Paid-in Capital [Member]
Private Placement [Member]
Additional Paid-in Capital [Member]
Public Offering [Member]
Additional Paid-in Capital [Member]
Private Investment in Public Equity (PIPE) [Member]
Accumulated Deficit [Member]
Other Comprehensive Income (Loss) [Member]
Balance, amount at Dec. 31, 2013           $ 56,155                          
Issuance of common stock, value   $ 61,241             $ 1         $ 61,240          
Balance, amount at Dec. 31, 2013 $ (63,479)                       $ 5,174         $ (68,653)  
Issuance of common stock, shares                 4,928,900                    
Balance, shares at Dec. 31, 2013           11,517,222                          
Balance, shares at Dec. 31, 2013             1,225,481                        
Conversion of convertible preferred stock to common stock in connection with initial public offering, amount 56,155         $ (56,155) $ 1           56,154            
Conversion of convertible preferred stock to common stock in connection with initial public offering, shares           (11,517,222) 11,517,222                        
Net exercise and conversion of preferred stock warrants to common stock in connection with initial public offering, amount 8,049                       8,049            
Net exercise and conversion of preferred stock warrants to common stock in connection with initial public offering, shares             571,244                        
Exercise of stock options and vesting of early exercised stock options, net of repurchases, amount $ 238                       238            
Exercise of stock options and vesting of early exercised stock options, net of repurchases, shares 336,398           336,398                        
Issuance of common stock for services, amount $ 208                       208            
Issuance of common stock for services, shares 10,000           10,000                        
Stock-based compensation $ 1,484                       1,484            
Net loss (3,214)                                 (3,214)  
Balance, amount at Dec. 31, 2014 60,682           $ 2           132,547         (71,867)  
Balance, shares at Dec. 31, 2014             18,589,245                        
Issuance of common stock, value     $ 74,323             $ 1         $ 74,322        
Issuance of common stock, shares                   7,242,992                  
Issuance of common stock under employee stock purchase plan ,amount 548                       548            
Issuance of common stock under employee stock purchase plan , shares             41,580                        
Exercise of stock options and vesting of early exercised stock options, net of repurchases, amount $ 111                       111            
Exercise of stock options and vesting of early exercised stock options, net of repurchases, shares 77,784           77,784                        
Issuance of common stock for services, amount $ 194                       194            
Issuance of common stock for services, shares 13,285           13,285                        
Stock-based compensation $ 2,634                       2,634            
Other 30                       30            
Net loss (29,621)                                 (29,621)  
Balance, amount at Dec. 31, 2015 108,901           $ 3           210,386         (101,488)  
Balance, shares at Dec. 31, 2015             25,964,886                        
Issuance of common stock, value       $ 80,837 $ 109,736           $ 1 $ 1       $ 80,836 $ 109,735    
Issuance of common stock, shares               5,000     8,625,000 12,600,230              
Issuance of common stock under employee stock purchase plan ,amount $ 576                       576            
Balance, shares at Dec. 31, 2015 25,964,886                                    
Issuance of common stock under employee stock purchase plan , shares             69,054                        
Exercise of stock options and vesting of early exercised stock options, net of repurchases, amount $ 55                       55            
Exercise of stock options and vesting of early exercised stock options, net of repurchases, shares 25,134           25,134                        
Issuance of common stock for services, amount $ 187                       187            
Issuance of common stock for services, shares 20,118           20,118                        
Stock-based compensation $ 5,317                       5,317            
Other comprehensive loss (71)                                   $ (71)
Net loss (112,387)                                 (112,387)  
Balance, amount at Dec. 31, 2016 $ 193,151           $ 5           $ 407,092         $ (213,875) $ (71)
Balance, shares at Dec. 31, 2016             47,309,422