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Selected Quarterly Financial Data (Unaudited) - Schedule of Selected Quarterly Financial Results from Operations (Detail) - USD ($) $ / shares in Units, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2015	Sep. 30, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Quarterly Financial Information Disclosure [Abstract]
Total revenue							$ 18,143	$ 5,883		$ 24,026	$ 31,623
Operating expenses	$ 31,476	$ 29,200	$ 28,690	$ 23,529	$ 16,876	$ 18,079	9,087	9,373	$ 112,895	53,415	33,187
Net (loss) income	$ (31,276)	$ (29,031)	$ (28,613)	$ (23,467)	$ (17,000)	$ (18,126)	$ 9,007	$ (3,502)	$ (112,387)	$ (29,621)	$ (3,214)
Net (loss) income per share:
Basic and Diluted	$ (0.66)	$ (0.65)	$ (0.83)	$ (0.70)					$ (2.80)	$ (1.29)	$ (0.31)
Basic					$ (0.65)	$ (0.70)	$ 0.43	$ (0.19)
Diluted					$ (0.65)	$ (0.70)	$ 0.42	$ (0.19)

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The amount of net income (loss) for the period per each share of common stock or unit outstanding during the reporting period.

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