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Accrued and Other Liabilities - Schedule of Accrued Liabilities and Other Liabilities (Detail) - USD ($)
$ in Thousands
Mar. 31, 2017
Dec. 31, 2016
Payables and Accruals [Abstract]    
Accrued clinical trial expenses $ 7,517 $ 6,694
Accrued contract manufacturing 3,010 2,705
Accrued professional and consulting services 391 322
Other 647 684
Accrued liabilities and other liabilities $ 11,565 $ 10,405 [1]
[1] Derived from the audited financial statements included in the Company's Annual Report on Form 10-K for the year ended December 31, 2016.