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Accrued and Other Liabilities - Schedule of Accrued Liabilities and Other Liabilities (Detail) - USD ($) $ in Thousands | Jun. 30, 2018 | Dec. 31, 2017
--- | --- | ---
Accrued and Other Liabilities |  |  |
Accrued clinical and non-clinical expenses | $ 5,518 | $ 5,447 |
Accrued contract manufacturing | 1,958 | 3,980 |
Derivative liability | 546 |  |
Accrued professional and consulting services | 368 | 530 |
Other | 844 | 752 |
Accrued liabilities and other liabilities | $ 9,234 | $ 10,709 | [1]
[1] | Derived from the audited consolidated financial statements included in the Company’s Annual Report on Form 10K for the year ended December 31, 2017.

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