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v3.10.0.1

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2018 | Jun. 30, 2017
Operating activities |  |  |
Net loss | $ (39,310) |  | $ (53,729)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation expense | 1,343 |  | 1,242
Amortization of deferred financing costs | 59 |  | 325
Amortization of deferred compensation for services | 101 |  | 91
Amortization of premium on investment securities | (256) |  | 1
Stock-based compensation | 5,028 |  | 4,899
Non-cash interest expense relating to loan payable | 54 |  |
Changes in operating assets and liabilities: |  |  |
Accounts receivable | 10,766 |  |
Prepaid expenses and other assets | 1,192 |  | (2,961)
Accounts payable | (706) |  | (451)
Accrued compensation and benefits | (1,026) |  | (562)
Accrued and other liabilities | (2,064) |  | 498
Net cash used in operating activities | (24,819) |  | (50,647)
Investing activities |  |  |
Proceeds from maturities of investments | 56,050 |  | 75,434
Sales and redemptions of investments | 850 |  | 10,482
Purchases of investments | (119,021) |  | (44,748)
Purchases of property and equipment | (55) |  | (1,907)
Net cash (used in) provided by investing activities | (62,176) |  | 39,261
Financing activities |  |  |
Proceeds from loan payable, net of issuance costs | 49,292 |  |
Proceeds from underwritten public offering, net of issuance costs | 53,770 |  |
Proceeds from issuance of common stock under stock plans | 301 |  | 424
Net cash provided by financing activities | 103,363 |  | 424
Net decrease in cash and cash equivalents | 16,368 |  | (10,962)
Cash and cash equivalents at beginning of period | 75,383 | [1] | 74,598
Cash and cash equivalents at end of period | 91,751 |  | $ 63,636
Supplementary disclosure of non-cash financing information: |  |  |
Issuance of derivative in connection with issuance of loan payable | $ 546 |  |
[1] | Derived from the audited consolidated financial statements included in the Company’s Annual Report on Form 10K for the year ended December 31, 2017.

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