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Accrued and Other Liabilities - Schedule of Accrued Liabilities and Other Liabilities (Detail) - USD ($)
$ in Thousands
Jun. 30, 2018
Dec. 31, 2017
Accrued and Other Liabilities    
Accrued clinical and non-clinical expenses $ 5,518 $ 5,447
Accrued contract manufacturing 1,958 3,980
Derivative liability 546  
Accrued professional and consulting services 368 530
Other 844 752
Accrued liabilities and other liabilities $ 9,234 $ 10,709 [1]
[1] Derived from the audited consolidated financial statements included in the Company’s Annual Report on Form 10K for the year ended December 31, 2017.