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Accrued and Other Liabilities - Schedule of Accrued Liabilities and Other Liabilities (Detail) - USD ($) $ in Thousands | Sep. 30, 2018 | Dec. 31, 2017
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Accrued and Other Liabilities |  |  |
Accrued clinical and non-clinical expenses | $ 6,792 | $ 5,447 |
Accrued contract manufacturing expenses | 977 | 3,980 |
Accrued professional and consulting services | 627 | 530 |
Derivative liability for exit fee | 556 |  |
Foreign currency derivative contract | 46 |  |
Other | 976 | 752 |
Accrued liabilities and other liabilities | $ 9,974 | $ 10,709 | [1]
[1] | Derived from the audited consolidated financial statements included in the Company’s Annual Report on Form 10K for the year ended December 31, 2017.

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