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Collaboration and Licensing Agreements - Narrative (Details) ¥ in Billions | 1 Months Ended | 3 Months Ended | 6 Months Ended | 44 Months Ended | 73 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | ---
Nov. 30, 2019 USD ($) item | Mar. 31, 2018 USD ($) | Dec. 31, 2017 USD ($) | Nov. 30, 2017 USD ($) | Jun. 30, 2015 USD ($) | Jun. 30, 2021 USD ($) | Mar. 31, 2021 USD ($) | Jun. 30, 2020 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2020 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2021 USD ($) | Jun. 30, 2021 JPY (¥) | Dec. 31, 2020 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  | $ 1,412,000 |  |  | $ 1,412,000 |  | $ 1,412,000 | $ 1,412,000 |  | $ 4,177,000
Revenue |  |  |  |  |  | 1,313,000 |  | $ 1,836,000 | 7,895,000 | $ 3,049,000 |  |  |  |
Cost of revenue |  |  |  |  |  | 0 |  | 141,000 | 1,000,000 | 141,000 |  |  |  |
Licensing revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 3,000 |  | 706,000 | 5,005,000 | 706,000 |  |  |  |
Product supply revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 0 |  | 5,000 | 126,000 | 43,000 |  |  |  |
2019 KKC Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognized |  |  |  |  |  |  |  |  | 2,765,000 |  |  |  |  |
Deferred revenue |  |  |  |  |  | 1,412,000 |  |  | 1,412,000 |  | 1,412,000 | 1,412,000 |  | 4,177,000
2019 KKC Agreement | KKC |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront license fees | $ 10,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
First installment of upfront license fees | $ 5,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Term of payment of license fee, first installment | 30 days |  |  |  |  |  |  |  |  |  |  |  |  |
Second installment of upfront license fees | $ 5,000,000.0 |  |  |  |  |  |  |  |  |  |  |  |  |
Term of agreement | 2 years |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue recognized |  |  |  |  |  | 1,300,000 |  | 1,100,000 | 2,800,000 | 2,300,000 |  |  |  |
Deferred revenue |  |  |  |  |  | 1,400,000 |  |  | 1,400,000 |  | 1,400,000 | 1,400,000 |  | $ 4,200,000
2019 KKC Agreement | KKC | Minimum |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of separate collaborative agreements | item | 1 |  |  |  |  |  |  |  |  |  |  |  |  |
2017 KKC Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Prepayment due |  |  |  |  |  | 2,900,000 |  |  | 2,947,000 |  |  |  |  |
2017 KKC Agreement | Licensing revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 0 | $ 5,000,000.0 | 0 | 5,000,000.0 | 0 | 10,000,000.0 |  |  |
2017 KKC Agreement | Product supply revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 0 |  |  | 100,000 |  |  |  |  |
2017 KKC Agreement | Other revenue |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  |  | 5,000.0 |  | 43,000.0 |  |  |  |
2017 KKC Agreement | KKC |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront license fees |  |  |  | $ 30,000,000.0 |  |  |  |  |  |  |  |  |  |
Potential development milestones |  |  |  | $ 55,000,000.0 |  |  |  |  |  |  |  |  |  |
Potential commercialization milestones |  |  |  |  |  | 76,500,000 |  |  | 76,500,000 |  | $ 76,500,000 | 76,500,000 | ¥ 8.5 |
Fosun Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 0 |  |  | 0 |  |  |  |  |
Fosun Agreement | Fosun Pharma |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment received |  |  | $ 12,000,000.0 |  |  |  |  |  |  |  |  |  |  |
Potential development and commercialization milestones |  |  |  |  |  |  |  |  | $ 110,000,000.0 |  |  |  |  |
Threshold percentage of net sales for tiered royalties |  |  |  |  |  |  |  |  | 20.00% |  |  |  |  |
Knight Agreement | Knight |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment received |  | $ 2,300,000 |  |  |  |  |  |  |  |  |  |  |  |
Potential development and commercialization milestones |  | $ 17,900,000 |  |  |  |  |  |  |  |  |  |  |  |
AstraZeneca Termination Agreement | AstraZeneca |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of royalty revenue |  |  |  |  | 10.00% |  |  |  |  |  |  |  |  |
Percentage of non-royalty revenue |  |  |  |  | 20.00% |  |  |  |  |  |  |  |  |
Maximum potential payment per agreement |  |  |  |  | $ 75,000,000.0 |  |  |  |  |  |  |  |  |
Cost of revenue |  |  |  |  |  | $ 0 |  | $ 100,000 | $ 1,000,000.0 | $ 100,000 |  | 11,600,000 |  |
Payments made per agreement |  |  |  |  |  |  |  |  |  |  |  | $ 10,600,000 |  |

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