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Restructuring (Details) - Workforce realignment $ in Millions |  |  | 3 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Nov. 30, 2021 lease_agreement | Oct. 12, 2021 employee | Dec. 31, 2021 USD ($) employee | Sep. 30, 2021 employee | Dec. 31, 2021 USD ($)
Restructuring Cost and Reserve [Line Items] |  |  |  |  |
Reduction in workforce | employee |  |  | 72 | 83 |
Reduction in workforce (percent) |  |  |  | 33.00% |
Notice period for impacted employees cash payments and benefits |  |  |  | 60 days |
Additional planned reduction in workforce | employee |  | 100 |  |  |
Additional planned reduction in workforce (percent) |  | 60.00% |  |  |
Previously eliminated positions retained | lease_agreement | 28 |  |  |  |
Restructuring charges |  |  |  |  | $ 6.2
Estimated restructuring liability |  |  | $ 0.5 |  | 0.5
Research and development expenses |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |
Restructuring charges |  |  |  |  | 2.7
General and administrative expense |  |  |  |  |
Restructuring Cost and Reserve [Line Items] |  |  |  |  |
Restructuring charges |  |  |  |  | $ 3.5

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- Definition The number of positions eliminated during the period as a percentage of total positions eliminated during the period in connection with the restructuring plan(s). + References No definition available. + Details
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- Definition Amount of expenses associated with exit or disposal activities pursuant to an authorized plan. Excludes expenses related to a discontinued operation or an asset retirement obligation. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 420 -SubTopic 10 -Section 45 -Paragraph 3 -URI http://asc.fasb.org/extlink&oid=109237686&loc=d3e17752-110868 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 420 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 5.P.3) -URI http://asc.fasb.org/extlink&oid=115931487&loc=d3e140864-122747 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585 Reference 4: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 420 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SAB Topic 5.P.4(b)(1)) -URI http://asc.fasb.org/extlink&oid=115931487&loc=d3e140904-122747 + Details
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