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Net Loss Per Share | 12 Months Ended
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Dec. 31, 2021
Earnings Per Share [Abstract] |
Net Loss Per Share | NET LOSS PER SHARE Basic net loss per share is calculated by dividing net loss by the weighted-average number of common shares outstanding during the period, less shares subject to repurchase, and excludes any dilutive effects of stock-based awards and warrants. Diluted net loss per common share is computed giving effect to all potential dilutive common shares, including common stock issuable upon exercise of stock options, and unvested restricted common stock and stock units. As we had net losses for the years ended December 31, 2021, 2020 and 2019, all potential common shares were determined to be anti-dilutive. The following table sets forth the computation of net loss per common share (in thousands, except per share amounts):
| Year Ended December 31,
| 2021 |  | 2020 |  | 2019
Numerator: |  |  |  |  |
Net loss | $ | (158,165) |  |  | $ | (94,313) |  |  | $ | (94,940) |
Denominator: |  |  |  |  |
Weighted average common shares outstanding - basic and diluted | 104,205,645 |  |  | 89,582,138 |  |  | 64,478,066 |
Net loss per share - basic and diluted | $ | (1.52) |  |  | $ | (1.05) |  |  | $ | (1.47) |
For the years ended December 31, 2021, 2020 and 2019, the total numbers of securities that could potentially dilute net income per share in the future that were not considered in the diluted net loss per share calculations because the effect would have been anti-dilutive were as follows:
| Year Ended December 31,
| 2021 |  | 2020 |  | 2019
Options to purchase common stock | 11,870,778 |  |  | 9,246,047 |  |  | 7,128,247 |
Restricted stock units | 1,602,384 |  |  | 26,121 |  |  | — |
ESPP shares issuable | 206,522 |  |  | 94,466 |  |  | 78,761 |
Warrants to purchase common stock | — |  |  | 932,091 |  |  | 2,172,899 |
Performance-based restricted stock units | — |  |  | — |  |  | 867,506 |
Total | 13,679,684 |  |  | 10,298,725 |  |  | 10,247,413 |
The number of potential common shares that would have been included in diluted income per share had it not been for the anti-dilutive effect caused by the net loss, computed by converting these securities using the treasury stock method during the years ended December 31, 2021, 2020 and 2019, was approximately 1.1 million, 2.1 million and 1.1 million, respectively.

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