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Net Loss Per Share
 12 Months Ended
Dec. 31, 2021
Earnings Per Share [Abstract]  
Net Loss Per Share NET LOSS PER SHARE
Basic net loss per share is calculated by dividing net loss by the weighted-average number of common shares outstanding during the period, less shares subject to repurchase, and excludes any dilutive effects of stock-based awards and warrants. Diluted net loss per common share is computed giving effect to all potential dilutive common shares, including common stock issuable upon exercise of stock options, and unvested restricted common stock and stock units. As we had net losses for the years ended December 31, 2021, 2020 and 2019, all potential common shares were determined to be anti-dilutive.
The following table sets forth the computation of net loss per common share (in thousands, except per share amounts):
Year Ended December 31,
202120202019
Numerator:
Net loss$(158,165)$(94,313)$(94,940)
Denominator:
Weighted average common shares outstanding - basic and diluted104,205,645 89,582,138 64,478,066 
Net loss per share - basic and diluted$(1.52)$(1.05)$(1.47)
For the years ended December 31, 2021, 2020 and 2019, the total numbers of securities that could potentially dilute net income per share in the future that were not considered in the diluted net loss per share calculations because the effect would have been anti-dilutive were as follows:
Year Ended December 31,
202120202019
Options to purchase common stock11,870,778 9,246,047 7,128,247 
Restricted stock units1,602,384 26,121 — 
ESPP shares issuable206,522 94,466 78,761 
Warrants to purchase common stock— 932,091 2,172,899 
Performance-based restricted stock units— — 867,506 
Total13,679,684 10,298,725 10,247,413 
The number of potential common shares that would have been included in diluted income per share had it not been for the anti-dilutive effect caused by the net loss, computed by converting these securities using the treasury stock method during the years ended December 31, 2021, 2020 and 2019, was approximately 1.1 million, 2.1 million and 1.1 million, respectively.