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Income Taxes (Tables)

12 Months Ended

Dec. 31, 2021

Income Tax Disclosure [Abstract]

Schedule of Components of Provision for Income Taxes

The components of our provision for income taxes for the year ended December 31, 2021, 2020 and 2019, are as follows (in thousands):

			Year Ended December 31,
			2021						2020						2019
Current:
State			$	4					$	2					$	2
Foreign			—						—						301
Total current			4						2						303
Deferred:
Federal			—						—						—
Total deferred			—						—						—
Provision for income taxes			$	4					$	2					$	303

Schedule of Reconciliation of Effective Tax Rate

The following is a reconciliation of the statutory federal income tax rate to our effective tax rate:

			Year Ended December 31,
			2021						2020						2019
Change in valuation allowance			(20.0)		%				(22.3)		%				(21.9)		%
Income tax at the federal statutory rate			21.0						21.0						21.0
Tax credits			1.0						1.3						1.6
State taxes, net of federal benefit			0.4						0.7						0.3
Stock based compensation			(1.3)						(0.1)						(0.4)
Executive compensation disallowed under IRC Sec 162(m)			(1.1)						(0.5)						(0.5)
Other			—						(0.1)						(0.4)
Income tax provision			—		%				—		%				(0.3)		%

Schedule of Components of Deferred Tax Assets

Significant components of our deferred tax assets are as follows as of December 31, 2021 and 2020 (in thousands):

			December 31,
			2021						2020
Deferred tax assets:
Amortization and depreciation			$	61,098					$	51,370
Net operating loss carryforwards			74,989						53,436
Tax credits			13,827						11,777
Stock-based compensation			4,054						5,524
Other			3,867						1,804
Gross deferred tax assets			157,835						123,911
Valuation allowance			(155,141)						(123,402)
Deferred tax assets net of valuation allowance			2,694						509
Deferred tax liabilities:
Right-of-use asset			(2,689)						(479)
Other			(5)						(30)
Net deferred tax assets			$	—					$	—

Schedule of Reconciliation of Unrecognized Tax Benefits

A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows (in thousands):

			December 31,
			2021						2020						2019
Balance at beginning of year			$	23,624					$	24,538					$	23,052
Additions (subtractions) based on tax positions related to prior year			(811)						(1,388)						755
Additions based on tax positions related to current year			1,613						474						731
Balance at end of year			$	24,426					$	23,624					$	24,538

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Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years.

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Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets.

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Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations.

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