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Net Loss Per Share (Tables)
12 Months Ended
Dec. 31, 2021
Earnings Per Share [Abstract]  
Schedule of Computation of Net Loss Per Common Share
The following table sets forth the computation of net loss per common share (in thousands, except per share amounts):
Year Ended December 31,
202120202019
Numerator:
Net loss$(158,165)$(94,313)$(94,940)
Denominator:
Weighted average common shares outstanding - basic and diluted104,205,645 89,582,138 64,478,066 
Net loss per share - basic and diluted$(1.52)$(1.05)$(1.47)
Schedule of Anti-Dilutive Securities Not Considered in Diluted Net Loss Per Common Share Calculation
For the years ended December 31, 2021, 2020 and 2019, the total numbers of securities that could potentially dilute net income per share in the future that were not considered in the diluted net loss per share calculations because the effect would have been anti-dilutive were as follows:
Year Ended December 31,
202120202019
Options to purchase common stock11,870,778 9,246,047 7,128,247 
Restricted stock units1,602,384 26,121 — 
ESPP shares issuable206,522 94,466 78,761 
Warrants to purchase common stock— 932,091 2,172,899 
Performance-based restricted stock units— — 867,506 
Total13,679,684 10,298,725 10,247,413