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Summary of Significant Accounting Policies - Liquidity (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Accounting Policies [Abstract]
Cash and investments	$ 116,689	$ 188,598
Accumulated deficit	$ (712,930)	$ (554,765)

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Sum of investments and unrestricted cash as of the balance sheet date.

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The cumulative amount of the reporting entity's undistributed earnings or deficit.

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