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Stockholders' Equity (Details) - USD ($)
$ / shares in Units, shares in Thousands
1 Months Ended 2 Months Ended 3 Months Ended 5 Months Ended 12 Months Ended 14 Months Ended
Dec. 09, 2019
Nov. 22, 2019
Sep. 10, 2021
Jun. 18, 2021
Dec. 31, 2019
Dec. 31, 2021
Feb. 19, 2021
Dec. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2021
Aug. 31, 2021
Jul. 31, 2020
Subsidiary, Sale of Stock [Line Items]                            
Proceeds from issuance of common stock                 $ 101,146,000 $ 21,047,000 $ 0      
Common stock                            
Subsidiary, Sale of Stock [Line Items]                            
Maximum aggregate offering price                           $ 250,000,000
2020 Open Market Sales Agreement                            
Subsidiary, Sale of Stock [Line Items]                            
Common stock sold and issued (in shares)     3,300 4,000   7,700 8,200         23,300    
Weighted-average share price (in dollars per share)                       $ 4.30    
Offering sales commission (percent)                 3.00%          
Proceeds from issuance of common stock                       $ 100,000,000    
2020 Open Market Sales Agreement | Common stock                            
Subsidiary, Sale of Stock [Line Items]                            
Maximum aggregate offering price                           $ 100,000,000
2021 Open Market Sales Agreement                            
Subsidiary, Sale of Stock [Line Items]                            
Common stock sold and issued (in shares)               15,700            
Weighted-average share price (in dollars per share)               $ 1.60            
Offering sales commission (percent)               3.00%            
Proceeds from issuance of common stock               $ 25,000,000            
2021 Open Market Sales Agreement | Common stock                            
Subsidiary, Sale of Stock [Line Items]                            
Maximum aggregate offering price                         $ 150,000,000  
Underwritten public offering, including underwriter option                            
Subsidiary, Sale of Stock [Line Items]                            
Common stock sold and issued (in shares) 23,000                          
Gross proceeds from sale of stock         $ 143,800,000                  
Underwriting discounts, commissions, and offering expenses         8,900,000                  
Proceeds from issuance of common stock         $ 134,900,000                  
Underwritten public offering                            
Subsidiary, Sale of Stock [Line Items]                            
Common stock sold and issued (in shares) 20,000                          
Share price (in dollars per share) $ 6.25                          
Underwriter option                            
Subsidiary, Sale of Stock [Line Items]                            
Common stock sold and issued (in shares) 3,000                          
Underwriter option period 30 days                          
Private Placement                            
Subsidiary, Sale of Stock [Line Items]                            
Common stock sold and issued (in shares)   2,900                        
Share price (in dollars per share)   $ 6.96                        
Proceeds from issuance of common stock   $ 20,000,000