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Restructuring (Details) - Workforce realignment
$ in Millions
3 Months Ended 12 Months Ended
Nov. 30, 2021
lease_agreement
Oct. 12, 2021
employee
Dec. 31, 2021
USD ($)
employee
Sep. 30, 2021
employee
Dec. 31, 2021
USD ($)
Restructuring Cost and Reserve [Line Items]          
Reduction in workforce | employee     72 83  
Reduction in workforce (percent)       33.00%  
Notice period for impacted employees cash payments and benefits       60 days  
Additional planned reduction in workforce | employee   100      
Additional planned reduction in workforce (percent)   60.00%      
Previously eliminated positions retained | lease_agreement 28        
Restructuring charges         $ 6.2
Estimated restructuring liability     $ 0.5   0.5
Research and development expenses          
Restructuring Cost and Reserve [Line Items]          
Restructuring charges         2.7
General and administrative expense          
Restructuring Cost and Reserve [Line Items]          
Restructuring charges         $ 3.5