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Borrowing - Narrative (Details) - USD ($) |  | 6 Months Ended |  |
--- | --- | --- | --- | ---
Feb. 23, 2022 | Jun. 30, 2022 | May 31, 2018 | May 16, 2018
Debt Instrument [Line Items] |  |  |  |
Principal outstanding |  | $ 28,862,000 |  |
2018 Term Loan | Term Loan |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Term loan face amount |  |  |  | $ 50,000,000
Principal outstanding |  |  |  | $ 25,000,000
2022 Term Loan | Term Loan |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Final fee due upon maturity, acceleration, prepayment, or termination (percent) | 4.95% |  |  |
Loan agreement covenant, cash and cash equivalents as percentage of outstanding loan balance, minimum | 80.00% |  |  |
Loan agreement, covenant, cash and cash equivalents as percentage of outstanding loan balance, calculation period |  | 6 months |  |
Loan agreement covenant, net product revenue as percentage of outstanding loan balance, minimum | 60.00% |  |  |
Additional default interest rate | 4.00% |  |  |
2022 Term Loan | Term Loan | Prior to first anniversary of closing date |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Prepayment premium (as a percent) | 3.00% |  |  |
2022 Term Loan | Term Loan | After first anniversary through second anniversary of closing date |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Prepayment premium (as a percent) | 2.00% |  |  |
2022 Term Loan | Term Loan | After second anniversary to maturity date |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Prepayment premium (as a percent) | 1.00% |  |  |
2022 Term Loan | Term Loan | LIBOR |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Floating per annum rate (percent) | 7.95% |  |  |
Addition to floating per annum rate (percent) | 0.10% |  |  |
Term Loan A | Term Loan |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Proceeds from the sale of future royalties, net of issuance costs | $ 27,500,000 |  |  |
Payment term | 36 months |  |  |
Closing fee | $ 200,000 |  |  |
Term Loan B | Term Loan |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Remaining funding based on milestone achievement | 22,500,000 |  |  |
Future obligation upon loan funding or other events | $ 100,000 |  |  |
2018 Exit Fee |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Agreed amount for exit fee upon occurrence of certain conditions |  |  | $ 1,500,000 |
2022 Exit Fee |  |  |  |
Debt Instrument [Line Items] |  |  |  |
Exit fee (percent) | 2.00% |  |  |
Exit fee, net product revenue threshold | $ 100,000,000 |  |  |
Exit fee, term (in years) | 10 years |  |  |

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