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v3.22.2.2

Organization and Basis of Presentation (Details) $ in Thousands | 1 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Jun. 30, 2015 USD ($) | Sep. 30, 2022 USD ($) segment | Dec. 31, 2021 USD ($)
Organization, Consolidation and Presentation of Financial Statements [Abstract] |  |  |
Number of segments | segment |  | 1 |
Cash and investments |  | $ 90,623 | $ 116,689
Accumulated deficit |  | 790,832 | 712,930
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Accounts receivable |  | 5,208 | 502
AstraZeneca | AZ Termination Agreement |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Percentage of royalty revenue | 10.00% |  |
Percentage of non-royalty revenue | 20.00% |  |
Maximum potential payment per agreement | $ 75,000 |  |
Aggregate cost of revenue recognized |  | $ 12,400 |
Minimum |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Payment terms |  | 30 days |
Maximum |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Payment terms |  | 60 days |
Collaborators |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Accounts receivable |  | $ 500 | $ 500
Commercial customers |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |
Accounts receivable |  | $ 4,700 |

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