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Collaboration and Licensing Agreements - Narrative (Details) $ in Millions, ¥ in Billions | 1 Months Ended | 3 Months Ended | 9 Months Ended | 59 Months Ended |  |
--- | --- | --- | --- | --- | --- | ---
Nov. 30, 2019 USD ($) segment item | Mar. 31, 2018 USD ($) | Dec. 31, 2017 USD ($) | Nov. 30, 2017 USD ($) | Jun. 30, 2015 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2022 CAD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2022 USD ($) | Sep. 30, 2022 JPY (¥) | Apr. 11, 2022 USD ($) payment_tranche
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | $ 4,986,000 | $ 1,173,000 | $ 7,980,000 |  | $ 9,068,000 |  |  |
Cost of revenue |  |  |  |  |  | 732,000 | 0 | 955,000 |  | 1,000,000 |  |  |
Licensing revenue |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 9,000 | 2,000 | 23,000 |  | 5,007,000 |  |  |
Product supply revenue |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 92,000 | 285,000 | 1,058,000 |  | 411,000 |  |  |
2019 KKC Agreement |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 0 | 900,000 | 0 |  | 3,700,000 |  |  |
2019 KKC Agreement | KKC |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront license fees | $ 10,000,000 |  |  |  |  |  |  |  |  |  |  |  |
First installment of upfront license fees | $ 5,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Term of payment of license fee, first installment | 30 days |  |  |  |  |  |  |  |  |  |  |  |
Second installment of upfront license fees | $ 5,000,000 |  |  |  |  |  |  |  |  |  |  |  |
Term of agreement | 2 years |  |  |  |  |  |  |  |  |  |  |  |
Number of amendments | segment | 3 |  |  |  |  |  |  |  |  |  |  |  |
2017 KKC Agreement | Licensing revenue |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 0 | 0 | 0 |  | 5,000,000 | $ 10,000,000 |  |
2017 KKC Agreement | Product supply revenue |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 83,000 | 300,000 | 1,000,000 |  | 400,000 |  |  |
2017 KKC Agreement | KKC |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront license fees |  |  |  | $ 30,000,000 |  |  |  |  |  |  |  |  |
Potential development milestones |  |  |  | $ 55,000,000 |  |  |  |  |  |  |  |  |
Potential commercialization milestones |  |  |  |  |  | 58,700,000 |  | 58,700,000 |  |  | 58,700,000 | ¥ 8.5 |
Fee receivable for reduction in royalty rate |  |  |  |  |  |  |  |  |  |  |  |  | $ 40,000,000
Number of payment tranches for fee receivable for reduction in royalty rate | payment_tranche |  |  |  |  |  |  |  |  |  |  |  |  | 2
Fosun Agreement |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  | 0 |  |  | 0 |  |  |
Fosun Agreement | Product supply revenue |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 9,000 |  | 9,000 |  |  |  |  |
Fosun Agreement | Fosun Pharma |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Potential development milestones |  |  |  |  |  | 3,000,000 |  | 3,000,000 |  |  | 3,000,000 |  |
Upfront payment received |  |  | $ 12,000,000 |  |  |  |  |  |  |  |  |  |
Potential development and commercialization milestones |  |  |  |  |  |  |  | $ 113,000,000 |  |  |  |  |
Threshold percentage of net sales for tiered royalties |  |  |  |  |  |  |  | 20.00% | 20.00% |  |  |  |
Knight Agreement |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  |  | 2,000 |  |  | 7,000 |  |  |
Knight Agreement | Licensing revenue |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Revenue |  |  |  |  |  | 9,000 |  | $ 23,000 |  |  |  |  |
Knight Agreement | Knight |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Potential development milestones |  |  |  |  |  | 700,000 |  | 700,000 |  |  | 700,000 |  |
Upfront payment received |  | $ 2,300,000 |  |  |  |  |  |  |  |  |  |  |
Potential development and commercialization milestones |  |  |  |  |  |  |  | 16,100,000 | $ 22.2 |  |  |  |
AZ Termination Agreement | AstraZeneca |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Percentage of royalty revenue |  |  |  |  | 10.00% |  |  |  |  |  |  |  |
Percentage of non-royalty revenue |  |  |  |  | 20.00% |  |  |  |  |  |  |  |
Maximum potential payment per agreement |  |  |  |  | $ 75,000,000 |  |  |  |  |  |  |  |
Aggregate cost of revenue recognized |  |  |  |  |  | 12,400,000 |  | 12,400,000 |  |  | 12,400,000 |  |
Aggregate amount paid |  |  |  |  |  | 11,600,000 |  | 11,600,000 |  |  | $ 11,600,000 |  |
Cost of revenue |  |  |  |  |  | $ 500,000 | $ 0 | $ 800,000 |  | $ 1,000,000 |  |  |
Minimum | 2019 KKC Agreement | KKC |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Number of separate collaborative agreements | item | 1 |  |  |  |  |  |  |  |  |  |  |  |

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