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CONDENSED STATEMENTS OF CHANGES IN STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Income
Beginning balance (in shares) at Dec. 31, 2020   93,599,975      
Beginning balance at Dec. 31, 2020 $ 126,112 $ 9 $ 680,872 $ (554,765) $ (4)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   386,664      
Issuance of common stock under employee stock purchase plan 819   819    
Issuance of common stock for services (in shares)   25,989      
Issuance of common stock for services 190   190    
Issuance of common stock upon exercise of options (in shares)   331,310      
Issuance of common stock upon exercise of options 584   584    
Issuance of common stock upon vesting of restricted stock units (in shares)   114,194      
Taxes paid for net share settlement of equity awards (106)   (106)    
Issuance of common stock in at the market offering (in shares)   12,313,452      
Issuance of common stock in at the market offering 67,189 $ 2 67,187    
Stock-based compensation 8,568   8,568    
Unrealized (losses) gains on available-for-sale securities 7       7
Net loss (121,931)     (121,931)  
Ending balance (in shares) at Sep. 30, 2021   106,771,584      
Ending balance at Sep. 30, 2021 81,432 $ 11 758,114 (676,696) 3
Beginning balance (in shares) at Dec. 31, 2020   93,599,975      
Beginning balance at Dec. 31, 2020 126,112 $ 9 680,872 (554,765) (4)
Ending balance (in shares) at Dec. 31, 2021   130,182,535      
Ending balance at Dec. 31, 2021 82,617 $ 13 795,540 (712,930) (6)
Beginning balance (in shares) at Jun. 30, 2021   102,967,017      
Beginning balance at Jun. 30, 2021 117,569 $ 10 750,664 (633,109) 4
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   284,456      
Issuance of common stock under employee stock purchase plan 341   341    
Issuance of common stock for services (in shares)   25,989      
Issuance of common stock for services 190   190    
Issuance of common stock upon exercise of options (in shares)   126,004      
Issuance of common stock upon exercise of options 21   21    
Issuance of common stock upon vesting of restricted stock units (in shares)   34,410      
Taxes paid for net share settlement of equity awards (106)   (106)    
Issuance of common stock in at the market offering (in shares)   3,333,708      
Issuance of common stock in at the market offering 4,743 $ 1 4,742    
Stock-based compensation 2,262   2,262    
Unrealized (losses) gains on available-for-sale securities (1)       (1)
Net loss (43,587)     (43,587)  
Ending balance (in shares) at Sep. 30, 2021   106,771,584      
Ending balance at Sep. 30, 2021 81,432 $ 11 758,114 (676,696) 3
Beginning balance (in shares) at Dec. 31, 2021   130,182,535      
Beginning balance at Dec. 31, 2021 82,617 $ 13 795,540 (712,930) (6)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   308,356      
Issuance of common stock under employee stock purchase plan 195   195    
Issuance of common stock for services (in shares)   711,675      
Issuance of common stock for services $ 390   390    
Issuance of common stock upon exercise of options (in shares) 0        
Issuance of common stock upon vesting of restricted stock units (in shares)   3,091,697      
Issuance of common stock in at the market offering (in shares)   53,105,382      
Issuance of common stock in at the market offering $ 52,845 $ 6 52,839    
Stock-based compensation 8,824   8,824    
Unrealized (losses) gains on available-for-sale securities (108)       (108)
Net loss (77,902)     (77,902)  
Ending balance (in shares) at Sep. 30, 2022   187,399,645      
Ending balance at Sep. 30, 2022 66,861 $ 19 857,788 (790,832) (114)
Beginning balance (in shares) at Jun. 30, 2022   153,797,834      
Beginning balance at Jun. 30, 2022 53,042 $ 15 821,075 (767,939) (109)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Issuance of common stock under employee stock purchase plan (in shares)   181,256      
Issuance of common stock under employee stock purchase plan 112   112    
Issuance of common stock for services (in shares)   711,675      
Issuance of common stock for services 390   390    
Issuance of common stock upon vesting of restricted stock units (in shares)   95,555      
Issuance of common stock in at the market offering (in shares)   32,613,325      
Issuance of common stock in at the market offering 34,367 $ 4 34,363    
Stock-based compensation 1,848   1,848    
Unrealized (losses) gains on available-for-sale securities (5)       (5)
Net loss (22,893)     (22,893)  
Ending balance (in shares) at Sep. 30, 2022   187,399,645      
Ending balance at Sep. 30, 2022 $ 66,861 $ 19 $ 857,788 $ (790,832) $ (114)