    <SEC-DOCUMENT>0001140361-23-020578-index.html : 20230426
    <SEC-HEADER>0001140361-23-020578.hdr.sgml : 20230426
    <ACCEPTANCE-DATETIME>20230426161846
    ACCESSION NUMBER:		0001140361-23-020578
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20221231
    FILED AS OF DATE:		20230426
    DATE AS OF CHANGE:		20230426
    EFFECTIVENESS DATE:		20230426

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ARDELYX, INC.
    		CENTRAL INDEX KEY:			0001437402
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				000000000
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36485
    		FILM NUMBER:		23849999

    	BUSINESS ADDRESS:
    		STREET 1:		34175 ARDENWOOD BLVD.
    		CITY:			FREMONT
    		STATE:			CA
    		ZIP:			94555
    		BUSINESS PHONE:		510-745-7047

    	MAIL ADDRESS:
    		STREET 1:		34175 ARDENWOOD BLVD.
    		CITY:			FREMONT
    		STATE:			CA
    		ZIP:			94555

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NTERYX INC
    		DATE OF NAME CHANGE:	20080611
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>ny20007204x3_ars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: ny20007204x3_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>