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Collaboration and Licensing Agreements (Tables) | 12 Months Ended
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Dec. 31, 2024
Collaboration and Licensing Agreements [Abstract] |
Schedule of Revenue | Disaggregation of total revenues by nature is as follows:
| Year Ended December 31, |  |  |  |
(in thousands) | 2024 |  | 2023 |  | 2022 |  |  |  |  |  |  |
Product sales, net | $ | 319,196 |  |  | $ | 82,526 |  |  | $ | 15,600 |  |  |  |  |  |  |  |  |
Product supply revenue | 11,649 |  |  | 6,121 |  |  | 1,527 |  |  |  |  |  |  |  |  |
Licensing revenue | 78 |  |  | 35,809 |  |  | 35,031 |  |  |  |  |  |  |  |  |
Non-cash royalty revenue related to the sale of future royalties | 2,692 |  |  | — |  |  | — |  |  |  |  |  |  |  |  |
Total revenues | $ | 333,615 |  |  | $ | 124,456 |  |  | $ | 52,158 |  |  |  |  |  |  |  |  |
Total product sales, net was as follows:
| Year Ended December 31, |  |  |  |
(in thousands) | 2024 |  | 2023 |  | 2022 |  |  |  |  |  |  |
Product sales, net |  |  |  |  |  |  |  |  |  |  |  |  |
IBSRELA | $ | 158,286 |  |  | $ | 80,062 |  |  | $ | 15,600 |  |  |  |  |  |  |  |  |
XPHOZAH | 160,910 |  |  | 2,464 |  |  | — |  |  |  |  |  |  |  |  |
Total product sales, net | $ | 319,196 |  |  | $ | 82,526 |  |  | $ | 15,600 |  |  |  |  |  |  |  |  |
The following table summarizes total revenue by collaboration partner:
| Year Ended December 31,
(in thousands) | 2024 |  | 2023 |  | 2022
Licensing revenue |  |  |  |  |
Kyowa Kirin | $ | — |  |  | $ | 30,000 |  |  | $ | 35,000 |
Fosun Pharma | — |  |  | 5,000 |  |  | — |
METiS | — |  |  | 750 |  |  | — |
Knight | 78 |  |  | 59 |  |  | 31 |
Total licensing revenue | $ | 78 |  |  | $ | 35,809 |  |  | $ | 35,031 |
Product supply revenue |  |  |  |  |
Kyowa Kirin | 11,649 |  |  | 6,092 |  |  | 1,518 |
Fosun Pharma | — |  |  | 29 |  |  | 9 |
Total supply revenue | $ | 11,649 |  |  | $ | 6,121 |  |  | $ | 1,527 |
Non-cash royalty revenue related to the sale of future royalties |  |  |  |  |
Kyowa Kirin | $ | 2,692 |  |  | $ | — |  |  | $ | — |
Schedule of Deferred Revenue Balances | The following table presents changes in our current and non-current deferred revenue balances, which are all attributable to Kyowa Kirin:
| 2024 |  | 2023
(in thousands) | Current |  | Non-Current |  | Current |  | Non-Current
Balance at January 1, | $ | 7,182 |  | $ | 8,644 |  | $ | 4,211 |  | $ | 9,025
Prepaid product supply | 3,716 |  | 8,212 |  | 1,547 |  | 5,629
Product supply delivered | (9,836) |  | — |  | (4,586) |  | —
Reclassify amounts to be recognized in the next twelve months | 9,624 |  | (9,624) |  | 6,010 |  | (6,010)
Balance at December 31, | $ | 10,686 |  | $ | 7,232 |  | $ | 7,182 |  | $ | 8,644

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