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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Operating activities    
Net loss $ (41,144) $ (26,518)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation and amortization expense 602 435
Non-cash lease expense 923 948
Stock-based compensation 12,088 7,616
Non-cash interest expense 2,136 1,753
Non-cash royalty revenue related to the sale of future royalties (1,026) (368)
Other, net (1,191) (1,265)
Changes in operating assets and liabilities    
Accounts receivable 11,238 (6,131)
Inventory (14,692) (29,371)
Prepaid commercial manufacturing (716) 13,406
Prepaid expenses and other assets (5,022) (5,450)
Accounts payable (2,278) 6,139
Accrued compensation and benefits (7,772) (5,870)
Operating lease liabilities (991) (1,068)
Accrued and other liabilities 8,043 7,159
Deferred revenue 1,345 2,863
Net cash used in operating activities (38,457) (35,722)
Investing activities    
Proceeds from maturities and redemptions of investments 34,726 31,602
Purchases of investments (31,550) (34,024)
Purchases of property and equipment (325) (150)
Net cash provided by (used in) investing activities 2,851 (2,572)
Financing activities    
Proceeds from 2022 Loan Agreement, net of issuance costs 0 49,750
Proceeds from issuance of common stock under equity incentive and stock purchase plans 1,482 3,221
Net cash provided by financing activities 1,482 52,971
Net (decrease) increase in cash and cash equivalents (34,124) 14,677
Cash and cash equivalents at beginning of period 64,932 21,470
Cash and cash equivalents at end of period 30,808 36,147
Supplementary disclosure of cash flow information    
Cash paid for interest 2,454 2,095
Cash paid for income taxes 2 1
Supplementary disclosure of non-cash activities    
Right-of-use assets obtained in exchange for lease obligations $ 2,213 $ 0