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COLLABORATION AND LICENSING AGREEMENTS (Tables) | 9 Months Ended
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Sep. 30, 2025
Collaboration and Licensing Agreements |
Schedule of Revenue | Disaggregation of total revenues by nature is as follows:
| Three Months Ended September 30, |  | Nine Months Ended September 30,
(in thousands) | 2025 |  | 2024 |  | 2025 |  | 2024
Product sales, net | $ | 105,515 |  |  | $ | 92,090 |  |  | $ | 263,406 |  |  | $ | 208,193 |
Product supply revenue | — |  |  | 5,322 |  |  | 6,439 |  |  | 7,461 |
Licensing revenue | 25 |  |  | 20 |  |  | 5,065 |  |  | 56 |
Non-cash royalty revenue related to the sale of future royalties | 4,789 |  |  | 809 |  |  | 7,195 |  |  | 1,776 |
Total revenues | $ | 110,329 |  |  | $ | 98,241 |  |  | $ | 282,105 |  |  | $ | 217,486 |
Total product sales, net was as follows:
| Three Months Ended September 30, |  | Nine Months Ended September 30,
(in thousands) | 2025 |  | 2024 |  | 2025 |  | 2024
Product sales, net |  |  |  |  |  |  |
IBSRELA | $ | 78,158 |  |  | $ | 40,638 |  |  | $ | 187,606 |  |  | $ | 104,444 |
XPHOZAH | 27,357 |  |  | 51,452 |  |  | 75,800 |  |  | 103,749 |
Total product sales, net | $ | 105,515 |  |  | $ | 92,090 |  |  | $ | 263,406 |  |  | $ | 208,193 |
Product sales, net as a percentage of total revenues | 95.6 | % |  | 93.7 | % |  | 93.4 | % |  | 95.7 | %
The following table summarizes total revenues by collaboration partner:
| Three Months Ended September 30, |  | Nine Months Ended September 30,
(in thousands) | 2025 |  | 2024 |  | 2025 |  | 2024
Licensing revenue |  |  |  |  |  |  |
Fosun Pharma | $ | — |  |  | $ | — |  |  | $ | 5,000 |  |  | $ | — |
Knight | 25 |  |  | 20 |  |  | 65 |  |  | 56 |
Total licensing revenue | $ | 25 |  |  | $ | 20 |  |  | $ | 5,065 |  |  | $ | 56 |
Product supply revenue |  |  |  |  |  |  |
Kyowa Kirin | $ | — |  |  | $ | 5,322 |  |  | $ | 6,185 |  |  | $ | 7,461 |
Knight | — |  |  | — |  |  | 254 |  |  | — |
Total supply revenue | $ | — |  |  | $ | 5,322 |  |  | $ | 6,439 |  |  | $ | 7,461 |
Non-cash royalty revenue related to the sale of future royalties |  |  |  |  |  |  |
Kyowa Kirin | $ | 4,789 |  |  | $ | 809 |  |  | $ | 7,195 |  |  | $ | 1,776 |
Schedule of Deferred Revenue Balances | The following table presents changes in our current and non-current deferred revenue balances, which are primarily attributable to Kyowa Kirin:
| 2025 |  | 2024
(in thousands) | Current |  | Non-Current |  | Current |  | Non-Current
Deferred revenue balance as of January 1, | $ | 10,686 |  | $ | 7,232 |  | $ | 7,182 |  | $ | 8,644
Prepaid product supply | 528 |  | 6,467 |  | 2,654 |  | 8,212
Product supply delivered | (4,633) |  | — |  | (6,650) |  | —
Reclassify amounts to be recognized in the next twelve months | — |  | — |  | 4,086 |  | (4,086)
Deferred revenue balance as of September 30, | $ | 6,581 |  | $ | 13,699 |  | $ | 7,272 |  | $ | 12,770

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