<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>poa.txt
<TEXT>


                               POWER OF ATTORNEY
     Know all by these presents, that the undersigned hereby constitutes and
     appoints each of (i) the Chief Executive Officer of Ardelyx, Inc., a
     Delaware corporation (the "Company"), who is currently Michael Raab, (ii)
     the Company's Principal Financial Officer, who is currently Justin Renz,
     (iii) the Company's Principal Accounting Officer, who is currently, Joseph
     Reilly, (iv)  the Senior Vice President of Legal, who is currently Shannon
     Moesaa, and (v) the Chief Legal Officer, who is currently Elizabeth
     Grammer, and their respective successors, signing singly, with full power
     of substitution and resubstitution, as the undersigned's true and lawful
     attorney-in-fact to:
     (1)  execute  for  and  on  behalf  of  the  undersigned,  in  the
     undersigned's  capacity  as an officer and/or director of the Company,
     (a)  Schedules  13D  and  13G  in  accordance  with  Section 13 of the
     Securities  Exchange Act of 1934, as amended (the "Exchange Act"), and
     the  rules  thereunder,  (b)  Forms  3,  4 and 5 (including amendments
     thereto)  in  accordance  with  Section  16(a) of Exchange Act and the
     rules  and  regulations  thereunder,  (c)  Notices of Proposed Sale of
     Securities  Pursuant  to Rule 144 ("Form 144"), in accordance with the
     requirements  of Rule 144 under the Securities Act of 1933, as amended
     (the  "Securities  Act")  and  (d)  Form  ID,  Uniform Application for
     Access Codes to File on EDGAR;
     (2)  do  and  perform  any  and  all  acts  for  and  on behalf of the
     undersigned  which  may  be  necessary  or  desirable  to complete and
     execute  any  such Schedule 13D, Schedule 13G, Forms 3, 4, 5 or 144 or
     Form  ID,  or  any  amendment  thereto,  and  timely  file  such forms
     (including  amendments thereto) and application with the United States
     Securities  and  Exchange Commission and any stock exchange or similar
     authority; and
     (3)  take  any  other  action  of  any  type  whatsoever in connection
     with  the  foregoing  which,  in the opinion of such attorney-in-fact,
     may  be  of  benefit  to, in the best interest of, or legally required
     by,  the  undersigned, it being understood that the documents executed
     by  such  attorney-in-fact  on  behalf  of the undersigned pursuant to
     this  Power  of  Attorney shall be in such form and shall contain such
     terms  and  conditions  as  such  attorney-in-fact may approve in such
     attorney-in-fact's discretion.
          The  undersigned  hereby  grants  to  each  such attorney-in-fact full
power  and  authority  to  do and perform any and every act and thing whatsoever
requisite,  necessary  or proper to be done in the exercise of any of the rights
and  powers  herein  granted,  as  fully  to  all  intents  and  purposes as the
undersigned  might  or  could  do  if  personally  present,  with  full power of
substitution  and  resubstitution or revocation, hereby ratifying and confirming
all  that  such  attorney-in-fact,  or  such  attorney-in-fact's  substitute  or
substitutes,  shall  lawfully  do or cause to be done by virtue of this power of
attorney  and  the  rights  and  powers  herein  granted.  The  undersigned
acknowledges  that  the foregoing attorneys-in-fact, in serving in such capacity
at  the  request  of  the  undersigned,  are  not  assuming,  nor is the Company
assuming,  any  of  the undersigned's responsibilities to comply with Section 13
and 16 of the Exchange Act or Rule 144 under the Securities Act.
     The  undersigned  agrees  that  each  such attorney-in-fact herein may rely
entirely  on  information  furnished  orally or in writing by the undersigned to
such  attorney-in-fact.  The  undersigned  also  agrees  to  indemnify  and hold
harmless  the Company and each such attorney-in-fact against any losses, claims,
damages  or  liabilities (or actions in these respects) that arise out of or are
based  upon  any  untrue  statements  or  omission  of  necessary  facts  in the
information  provided  by  the undersigned to such attorney-in fact for purposes
of  executing,  acknowledging,  delivering  or  filing  Forms  3,  4,  5  or 144
(including  amendments  thereto)  or Form ID and agrees to reimburse the Company
and  such  attorney-in-fact  for any legal or other expenses reasonably incurred
in  connection  with  investigating  or  defending against any such loss, claim,
damage, liability or action.
     This  Power  of  Attorney  supersedes  any  power  of  attorney  previously
executed  by  the  undersigned  regarding  the  purposes  outlined  in the first
paragraph  hereof  ("Prior  Powers  of  Attorney"),  and  the  authority  of the
attorneys-in-fact named in any Prior Powers of Attorney is hereby revoked.
     This  Power  of  Attorney  shall  remain in full force and effect until the
undersigned  is no longer required to file Schedule 13D or 13G and Forms 3, 4, 5
or  144  with  respect  to  the  undersigned's  holdings  of and transactions in
securities  issued by the Company, unless earlier (a) revoked by the undersigned
in  a  signed  writing  delivered  to  the  foregoing  attorneys-in-fact  or (b)
superseded  by  a  new  power of attorney regarding the purposes outlined in the
first paragraph hereof dated as of a later date.
     IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to
be executed as of this  day of October 6, 2025.




                                         /S/ JOHN BISHOP



</TEXT>
</DOCUMENT>
