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  <xsd:element id="vrts_LineOfCreditFacilityIncreaseAdditionalBorrowingsOnConditionSatisfaction" name="LineOfCreditFacilityIncreaseAdditionalBorrowingsOnConditionSatisfaction" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_MarkYoungersvVirtusInvestmentPartnersIncetalMember" name="MarkYoungersvVirtusInvestmentPartnersIncetalMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_MarketableSecuritiesCost" name="MarketableSecuritiesCost" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="vrts_MarketableSecuritiesUnrealizedGain" name="MarketableSecuritiesUnrealizedGain" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="vrts_MarketableSecuritiesUnrealizedLosses" name="MarketableSecuritiesUnrealizedLosses" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="vrts_MaximumLeverageRatio" name="MaximumLeverageRatio" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_MinimumInterestCoverageRatioUnderCreditFacility" name="MinimumInterestCoverageRatioUnderCreditFacility" nillable="true" substitutionGroup="xbrli:item" type="xbrli:pureItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_NetIncomeLossAvailableToCommonStockholdersAfterAdjustments" name="NetIncomeLossAvailableToCommonStockholdersAfterAdjustments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vrts_NetInterestInInvestmentProducts" name="NetInterestInInvestmentProducts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="vrts_NetInterestinInvestmentProductsPercentageofTotalInvestmentsofInvestmentProducts" name="NetInterestinInvestmentProductsPercentageofTotalInvestmentsofInvestmentProducts" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="vrts_NonCashFinancingActivitiesAbstract" name="NonCashFinancingActivitiesAbstract" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_NonQualifiedRetirementPlanAssetsAndLiabilitiesPolicyTextBlock" name="NonQualifiedRetirementPlanAssetsAndLiabilitiesPolicyTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_NoncontrollingInterestPolicyTextBlock" name="NoncontrollingInterestPolicyTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_NonqualifiedRetirementPlanAssetsMember" name="NonqualifiedRetirementPlanAssetsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_NumberOfAdditionalConsolidatedSponsoredInvestmentProducts" name="NumberOfAdditionalConsolidatedSponsoredInvestmentProducts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_NumberOfSponsoredInvestmentProductsConsolidated" name="NumberOfSponsoredInvestmentProductsConsolidated" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="vrts_NumberOfSponsoredInvestmentProductsDeconsolidated" name="NumberOfSponsoredInvestmentProductsDeconsolidated" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_NumberofInvestmentProductsConsolidated" name="NumberofInvestmentProductsConsolidated" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="vrts_NumberofProductsConsolidated" name="NumberofProductsConsolidated" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="instant" />
  <xsd:element id="vrts_OtherNonoperatingIncomeExpenses" name="OtherNonoperatingIncomeExpenses" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vrts_PaymentOfWithholdingTaxesRelatedToRestrictedStock" name="PaymentOfWithholdingTaxesRelatedToRestrictedStock" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vrts_PaymentOnDebtAndDeferredFinancingCosts" name="PaymentOnDebtAndDeferredFinancingCosts" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vrts_PaymentsToAcquireAssetsAndOtherInvestments" name="PaymentsToAcquireAssetsAndOtherInvestments" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vrts_PercentageOfBorrowingsOnAssetsAvailableAsCollateral" name="PercentageOfBorrowingsOnAssetsAvailableAsCollateral" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_PercentageOfChangeInOwnership" name="PercentageOfChangeInOwnership" nillable="true" substitutionGroup="xbrli:item" type="num:percentItemType" xbrli:periodType="instant" />
  <xsd:element abstract="true" id="vrts_RedeemableNoncontrollingInterestMember" name="RedeemableNoncontrollingInterestMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_RestrictedStockUnitsRSUsPerformanceBasedMember" name="RestrictedStockUnitsRSUsPerformanceBasedMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_RevenueFromInvestmentManagementAdministrationAndTransferAgentFees" name="RevenueFromInvestmentManagementAdministrationAndTransferAgentFees" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vrts_SecuritiesPurchasedPayable" name="SecuritiesPurchasedPayable" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="vrts_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsIntrinsicValue" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsIntrinsicValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="duration" />
  <xsd:element id="vrts_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantDateFairValue" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantDateFairValue" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element id="vrts_SharebasedCompensationNumberofPerformanceMetrics" name="SharebasedCompensationNumberofPerformanceMetrics" nillable="true" substitutionGroup="xbrli:item" type="xbrli:integerItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_SharebasedCompensationbySharebasedPaymentAwardMeasurementPeriodForGrowthInOperatingIncome" name="SharebasedCompensationbySharebasedPaymentAwardMeasurementPeriodForGrowthInOperatingIncome" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_SharebasedCompensationbySharebasedPaymentAwardMeasurementPeriodForTotalShareholderReturnRelativetoPeers" name="SharebasedCompensationbySharebasedPaymentAwardMeasurementPeriodForTotalShareholderReturnRelativetoPeers" nillable="true" substitutionGroup="xbrli:item" type="xbrli:durationItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_SponsoredClosedEndFundsMember" name="SponsoredClosedEndFundsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_SponsoredFundsMember" name="SponsoredFundsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_StockBasedCompensationExpenseTableTextBlock" name="StockBasedCompensationExpenseTableTextBlock" nillable="true" substitutionGroup="xbrli:item" type="nonnum:textBlockItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_SummaryOfSignificantAccountingPoliciesLineItems" name="SummaryOfSignificantAccountingPoliciesLineItems" nillable="true" substitutionGroup="xbrli:item" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_SummaryOfSignificantAccountingPoliciesTable" name="SummaryOfSignificantAccountingPoliciesTable" nillable="true" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType" xbrli:periodType="duration" />
  <xsd:element id="vrts_TradingSecuritiesUnrealizedGain" name="TradingSecuritiesUnrealizedGain" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="instant" />
  <xsd:element id="vrts_TradingSecuritiesUnrealizedLoss" name="TradingSecuritiesUnrealizedLoss" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="credit" xbrli:periodType="instant" />
  <xsd:element id="vrts_UnamortizedStockBasedCompensationExpense" name="UnamortizedStockBasedCompensationExpense" nillable="true" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType" xbrli:balance="debit" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_VirtusETFSolutionsMember" name="VirtusETFSolutionsMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_VirtusEmergingMarketsOpportunitiesFundMember" name="VirtusEmergingMarketsOpportunitiesFundMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_VirtusInvestmentPartnersIncSecuritiesLitigationMember" name="VirtusInvestmentPartnersIncSecuritiesLitigationMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_VirtusMultiSectorShortTermBondFundMember" name="VirtusMultiSectorShortTermBondFundMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
  <xsd:element abstract="true" id="vrts_VirtusPremiumAlphaSectorFundMember" name="VirtusPremiumAlphaSectorFundMember" nillable="true" substitutionGroup="xbrli:item" type="nonnum:domainItemType" xbrli:periodType="duration" />
</xsd:schema>
