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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) (Parenthetical) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Jun. 30, 2024
Research and development | [1] | $ 22,680 | $ 15,689 | $ 42,252 | $ 28,193
General and administrative | [2] | 6,816 | 5,111 | 14,352 | 9,701
Third Rock Ventures LLC |  |  |  |  |
Research and development |  | 0 | 0 | 0 |
General and administrative |  | $ 0 | $ 0 | $ 0 | 100
Third Rock Ventures LLC | Maximum |  |  |  |  |
Research and development |  |  |  |  | $ 100
[1] | Includes related party amounts of zero for each of the three months ended June 30, 2025 and 2024, and zero and less than $0.1 million for the six months ended June 30, 2025 and 2024, respectively (see Note 10).
[2] | Includes related party amounts of zero for each of the three months ended June 30, 2025 and 2024, and zero and $0.1 million for the six months ended June 30, 2025 and 2024, respectively (see Note 10).

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