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Segment (Tables) | 6 Months Ended
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Jun. 30, 2025
Segment Reporting [Abstract] |
Summary of Reconciles Reported Revenues to Net (Loss) Income under Significant Expense Principle | The following table reconciles reported revenues to net (loss) income under the significant expense principle for the three and six months ended June 30, 2025 and 2024 (in thousands):
|  | For the Three Months Ended June 30, |  |  | For the Six Months Ended June 30, |
|  | 2025 |  |  | 2024 |  |  | 2025 |  |  | 2024 |
Research and Development Expenses: |  |  |  |  |  |  |  |  |  |  |  |
RAP-219 program external expenses |  | $ | 9,685 |  |  | $ | 4,846 |  |  | $ | 17,648 |  |  | $ | 8,747 |
Preclinical programs external expenses |  |  | 4,722 |  |  |  | 5,648 |  |  |  | 7,968 |  |  |  | 9,582 |
R&D personnel-related costs (including stock-based compensation) |  |  | 6,666 |  |  |  | 4,590 |  |  |  | 13,452 |  |  |  | 8,607 |
Other costs |  |  | 1,607 |  |  |  | 605 |  |  |  | 3,184 |  |  |  | 1,257 |
General and Administrative Expenses: |  |  |  |  |  |  |  |  |  |  |  |
G&A personnel-related costs (including stock-based compensation) |  |  | 5,045 |  |  |  | 3,436 |  |  |  | 10,004 |  |  |  | 5,833 |
Professional and consulting costs |  |  | 920 |  |  |  | 1,108 |  |  |  | 2,584 |  |  |  | 2,973 |
Facility related and other |  |  | 851 |  |  |  | 567 |  |  |  | 1,764 |  |  |  | 895 |
Loss from operations |  | $ | (29,496 | ) |  | $ | (20,800 | ) |  | $ | (56,604 | ) |  | $ | (37,894 | )
Interest income |  |  | 2,764 |  |  |  | 2,679 |  |  |  | 5,809 |  |  |  | 4,494 |
Change in fair value of preferred stock tranche right liability |  |  | — |  |  |  | — |  |  |  | — |  |  |  | (7,390 | )
Net loss |  | $ | (26,732 | ) |  | $ | (18,121 | ) |  | $ | (50,795 | ) |  | $ | (40,790 | )

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- Definition Tabular disclosure of the reconciliation of profit (loss) from reportable segments to the consolidated income (loss) before income tax expense (benefit) and discontinued operations. Includes, but is not limited to, reconciliation after income tax if income tax is allocated to the reportable segment. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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