v2.4.0.8
Summary of Significant Accounting Policies - Additional Information (Detail) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2013
Collaborator
Sep. 30, 2012
Sep. 30, 2013
Segment
Collaborator
Sep. 30, 2012
Dec. 31, 2012
Segment
Dec. 31, 2011
Organization And Significant Accounting Policies [Line Items]            
Research and development commitments with third parties $ 2,786   $ 2,786   $ 3,164 $ 6,220
Research and development commitments with third parties not incurred 1,267   1,267   1,431 1,665
Maturity period of liquid investment     3 months   3 months  
Cash equivalent investments in highly liquid money market accounts 56,693   56,693   9,384 18,833
Short-term investments 136,672   136,672   260 258
Fair value of financial assets measured at fair value on a recurring basis 325,348   325,348   83,376 39,097
Unrealized appreciation (depreciation) in the fair value of the Company's equity securities 27,339 (3,940) 5,704 12,031 (6,290) (2,675)
Carrying value of investment in VIEs 11,540   11,540   5,726  
Percentage of recognized income tax positions     50.00%   50.00%  
Number of segment     1   1  
Investments gross unrealized losses 9   9      
Number of collaborators identified as VIEs 2   2      
Equity Securities [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Fair value of financial assets measured at fair value on a recurring basis 107,567   107,567   83,116 39,097
Ziopharm [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Company's ownership percentage of Ziopharm 16.20%   16.20%   16.30% 11.50%
Ziopharm [Member] | Equity Securities [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Fair value of financial assets measured at fair value on a recurring basis 53,321   53,321   56,298 35,162
Unrealized appreciation (depreciation) in the fair value of the Company's equity securities 24,766 (4,948) (2,977) 8,773 (7,194) (4,924)
Certificates of Deposit [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Short-term investments         $ 260 $ 258
Minimum [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Maturity of certificate of deposits         3 Months  
Minimum [Member] | Patents and Related Technologies [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Period of estimated useful lives     7 years   7 years  
Minimum [Member] | Leasehold improvements [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Life of the asset     1 year   1 year  
Maximum [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Maturity of certificate of deposits         1 Year  
Maximum [Member] | Patents and Related Technologies [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Period of estimated useful lives     14 years   14 years  
Maximum [Member] | Leasehold improvements [Member]
           
Organization And Significant Accounting Policies [Line Items]            
Life of the asset     4 years   4 years