Exhibit 12.1

Intrexon Corporation

Computation of Ratio of Earnings to Fixed Charges and Ratio of Earnings to Combined Fixed Charges and Preferred Stock Dividends (1)

(in thousands)

 

     Six Months
Ended June 30,
    Year Ended December 31,  
     2014     2013     2012     2011  

Calculation of earnings (loss):

        

Pre-tax loss from continuing operations before adjustment for equity in net loss from equity method investments

     (47,772     (40,302     (82,148     (85,280

Add: Fixed charges (see below)

     989        1,999        1,734        1,515   
  

 

 

   

 

 

   

 

 

   

 

 

 

Total loss

     (46,783     (38,303     (80,414     (83,765
  

 

 

   

 

 

   

 

 

   

 

 

 

Fixed charges:

        

Interest expense

     (79     (141     (57     (183

Interest expense on portion of rent expense representative of interest

     (910     (1,858     (1,677     (1,332

Total fixed charges

     (989     (1,999     (1,734     (1,515

Ratio of earnings to fixed charges

     —   (2)      —   (2)     —   (2)      —   (2) 

Accretion of dividends on redeemable convertible preferred stock

           (18,391     (21,994     (13,868
  

 

 

   

 

 

   

 

 

   

 

 

 

Total combined fixed charges and preferred stock dividends

     (989     (20,390     (23,728     (15,383
  

 

 

   

 

 

   

 

 

   

 

 

 

Ratio of earnings to combined fixed charges and preferred stock dividends

     —   (3)      —   (3)      —   (3)      —   (3) 
  

 

 

   

 

 

   

 

 

   

 

 

 

 

(1) All outstanding shares of redeemable convertible preferred stock along with cumulative dividends that existed prior to our initial public offering in August 2013 were converted into shares of common stock in connection with our initial public offering. As of the date of this prospectus, no shares of preferred stock are outstanding.
(2) Earnings for the six months ended June 30, 2014, and for the years ended December 31, 2013, 2012 and 2011 were less than zero. As a result the coverage ratio was less than 1:1. The amounts of the deficiencies, or the additional earnings we would need to generate to achieve a coverage ratio of 1:1, were approximately $47,772, $40,302, $82,148 and $85,280, respectively, for the six months ended June 30, 2014, and for the years ended December 31, 2013, 2012 and 2011.
(3) Earnings for the six months ended June 30, 2014, and for the years ended December 31, 2013, 2012 and 2011 were less than zero. As a result the coverage ratio was less than 1:1. The amounts of the deficiencies, or the additional earnings we would need to generate to achieve a coverage ratio of 1:1, were approximately $47,772, $58,693, $104,142 and $99,148, respectively, for the six months ended June 30, 2014, and for the years ended December 31, 2013, 2012 and 2011. We had no preferred stock outstanding during the six months ended June 30, 2014.